Cardiology In Primary Care With Midge Bowers

 

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Show notes:

I am excited to introduce you to an absolute gem in the field of healthcare—Midge Bowers, Clinical Professor and Director of the Cardiovascular Specialty at Duke University School of Nursing.

She also actively practices as a nurse practitioner in a Heart Failure Access Clinic, with a unique blend of theoretical knowledge and hands-on experience.

In this jam-packed episode, we covered:

1. Beyond Creatinine Levels:

Assessing kidney function is crucial when it comes to cardiology. Midge emphasizes the importance of looking beyond creatinine levels when assessing kidney function. She sheds light on the significance of glomerular filtration rate (GFR) and its impact on patient care, especially in the context of newer medications like SGLT-2s.

2. Practical Insights into Echocardiograms:

Navigating through the complexities of echocardiogram reports can be daunting. Midge simplifies this process by focusing on practical aspects such as akinesia, hypokinesia, and ejection fraction (EF). Her concrete pearls of wisdom make understanding echo reports more accessible.

3. Demystifying Anticoagulation Choices:

Anticoagulation therapy often presents a dilemma for healthcare practitioners. Midge provides clarity on the decision-making process between Warfarin and Direct Oral Anticoagulants (DOACs). Her insights, drawn from real-world scenarios, empower practitioners to make informed choices.

4. Practical Tips on Adjusting Warfarin Dosages:

Managing Warfarin dosages can be challenging, but Midge breaks it down into actionable steps. It’s an important and common medication, and her guidance on INR interpretation and medication titration are easy and helpful.

5. Prescribing DOACs Safely:

Midge discusses safety measures and risk assessments using tools like CHADS-VASc and HAS-BLED, providing a comprehensive understanding of bleeding risks in anticoagulation therapy. She also covers DOAC prescribing and guidance on reversal agents. 

If you liked this post, also check out: 

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    Hey there, welcome to the Real World NP podcast.

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    I'm Liz Rohr, family nurse practitioner, educator, and founder of Real World NP, an educational

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    company for nurse practitioners in primary care.

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    I'm on a mission to equip and guide new nurse practitioners so that they can feel

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    confident, capable, and take the best care of their patients.

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    If you're looking for clinical pearls and practice tips without the fluff, you're in

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    the right place.

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    Make sure you subscribe and leave a review so you won't miss an episode.

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    Plus, you'll find links to all the episodes with extra goodies over at realworldnp.com

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    slash podcast.

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    So one of the things I have to say is I'm in my 25th year as an NP and you think,

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    oh my gosh, that's such a long time.

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    But Liz, I have to tell you, I learn something new every week because cardiology is so dynamic.

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    And I think like an FNP.

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    I think about the whole person, right?

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    All those social determinants of health, I think about prevention.

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    So medication, it's really important to me.

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    And I'm going to try to add medications to manage the conditions you see in your

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    practice.

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    Hypertension, AFib, heart failure, it's not just, I'm here for cardiology and

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    I don't care.

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    I actually do.

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    And I think the biggest thing I want folks to get out of this episode is that their

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    partners find a cardiology partner, physician, PA, NP, who you're OK like chatting with.

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    So I have a really, really delightful interview to share with you.

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    I know that I say this all the time, that I love these interviews, but I really,

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    really do. This person is a real gem.

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    Her name is Midge Bowers.

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    She's a cardiology NP, who is an educator and has over 20 years of experience.

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    I first met her at the AMP conference where she just gave this talk that was

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    phenomenal. She's just an excellent, excellent educator.

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    And yeah, I just feel like a kindred spirit.

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    So anyway, I want to share with you her bio and then I'll share my interview

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    with her. First, the topics that we talked about.

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    So first one, the topics that we talked about.

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    So we talked about heart failure, we talked about atrial fibrillation and we

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    talked about echoes.

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    But the main focus was really about medication, titration and like real

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    practical applied pieces.

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    And so I've done two different interviews, cardiology topics.

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    So one was about heart failure, kind of like all about what is guideline

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    directed medical therapy. What does that mean?

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    So definitely check that out if you're feeling like you want to

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    guidance about heart failure.

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    We addressed it as a cardiology interview with another nurse practitioner.

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    But the focus of this one is really like kind of taking some of those

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    things that we talked about and really like, what does that actually look

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    like in clinical practice?

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    So I think that's one of the reasons that I super love this episode.

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    In addition to Midge is just fantastic.

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    So yeah, so that's the episode, but let me read you her bio so you can

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    know a little bit more about her.

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    So Midge Bowers is a DNP, family nurse practitioner, and as well as a

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    cardiology practitioner, she talks a little bit about herself in her

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    intro, which she currently does, but her pronouns are she, her, hers.

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    She's a clinical professor and director of the cardiovascular specialty

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    at Duke University School of Nursing and practices as a nurse practitioner

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    in a heart failure access clinic.

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    Her scholarly work is focused on patients with cardiovascular diseases

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    in a professional education and simulation.

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    I wish I had her as a professor.

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    Honestly, she's amazing.

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    As an associate in the American college of cardiology and a certified

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    health simulation educator, she is the only nurse practitioner in the

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    leadership team of the ACC simulation council.

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    She's actively involved in the American association of nurse practitioners

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    and recognized as a fellow in AAMP and the American Academy of Nursing.

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    She is both extremely impressive on paper and in person.

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    She's just fantastic.

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    So I really can't wait to share this interview with you.

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    Awesome.

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    Thank you so much for being here.

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    I'm so excited.

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    Can you introduce yourself?

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    Sure.

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    My name is Dr.

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    Midge Bowers.

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    I'm a family nurse practitioner, a professor at Duke School of Nursing,

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    and I work one day a week in a cardiology outpatient practice that

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    focuses on caring for patients with heart failure.

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    That's awesome.

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    That's awesome.

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    Thank you so much.

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    And you and I talked off recording about how many different

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    cardiology topics there are.

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    It's just like, so I met you through a conference, through AAMP conference.

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    And yeah, I think I'm just really struck.

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    I think one of the things that I love about being a family nurse practitioner

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    and being in primary care is that we are like jack of all trades, but then

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    that comes at the kind of cost of master of none, you know?

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    And so I think that I just really appreciate it, especially from your

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    talk about cardiology topics is that there's just such a depth to it.

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    And there are so many things that one could talk about, right?

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    And you and I talked off camera about how I had a heart failure episode

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    and I talked with a different cardiology MP, but like, honestly,

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    the topics are endless and it is such a big part of primary care.

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    And so what we sort of talked about is the focuses on kind of the

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    first thing was about medication titration, because that's such a

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    huge thing for new nurse practitioners, but also myself experienced

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    nurse practitioners, people who are experienced in other

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    practices coming to primary care.

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    So tell me, where do you want to jump in with that topic?

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    Where do you, where do you want to go?

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    So one of the things I have to say is I've been in, I'm in my 25th

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    year as an MP and you think, Oh my gosh, that's such a long time.

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    But Liz, I have to tell you, I learned something new every week

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    because cardiology is so dynamic.

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    And I think like an FNP, I think about the whole person, right?

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    All those social determinants of health, I think about prevention.

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    So medication, it's a really important to me.

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    And I'm going to try to add medications to manage the

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    conditions you see in your practice.

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    Hypertension, a fib, heart failure.

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    It's not just a, I'm here for cardiology and I don't care.

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    I actually do.

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    And I think the biggest thing I want folks to get out of this

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    episode is that their partners find a cardiology partner,

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    physician, PA, NP, who you're okay, like chatting with.

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    Recently, I had like messages from a PA in a nursing home who

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    was concerned about diareasing.

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    So we had, neither of us had time to pick up the phone.

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    But we messaged through our electronic health record.

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    So I just encourage folks, like this was an offline, the

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    patient wasn't followed up Duke.

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    I said, if I was seeing a patient like this, right?

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    This is how I would manage the situation.

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    Totally, totally.

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    But that keeps me from my liability.

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    I didn't say do this, do this, do this, right?

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    Yes.

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    But, but ask for that consult peer to peer it.

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    And then, because sometimes you can't get in to the

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    other reality, right?

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    Yes.

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    Delay, delay, delay, delay, delay.

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    So that's just kind of one contextual thing I wanted to

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    put out there.

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    Yeah, I love that.

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    Because like, so I've talked a little bit, if people have

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    been listening to the podcast for a while, they may have

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    heard this, but that was one of the pieces of advice that

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    I got from one of my mentors when I first started was cold

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    calling and I was like, are you serious?

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    No way that's going to happen.

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    And I literally sat down with somebody and they were like,

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    do it right now, just call them.

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    And like you said, like, they might not have time to

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    have a conversation, but you can leave a detailed message.

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    You know, being careful about PHI, but like, what is

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    the detailed question that you have?

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    And like, is there some sort of way to connect with them?

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    Because they really do want to help, right?

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    Because like you can talk about the most recent trials

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    of all these medications and cardiology.

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    Like I can't read that stuff.

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    I don't have time for that stuff.

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    Right.

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    And if it's like a, you know, breaking thing, sure.

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    But like not to the depth that you will.

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    Right.

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    So it's just wonderful to hear that reinforced from

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    specialists.

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    Oh my gosh.

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    Well, I think about the patient that's going for a

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    transplant that all of a sudden is coming to my clinic for

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    cardiology clearance and they're on these meds.

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    And I'm like, I have no idea what this involves and what

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    I should stop and what I shouldn't stop.

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    And what is, what's their preop risk?

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    I have to look that up.

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    Right.

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    So 25 years into it, you still have to look it up.

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    Yeah.

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    It was like so fun.

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    I love that.

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    I mean, I hate it and I love it at the same time.

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    Exactly, exactly.

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    But you weren't, what I want to value is the

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    breadth of an FNP's role.

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    Right.

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    Just recently, I was doing simulations for adult patients

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    on, you know, PEA arrest.

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    And these were acute care NPs.

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    And then the next day I was doing cardiogenic shock in a

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    four month old.

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    So in my head, I was like, well, dang, I know how to

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    calculate the blood pressure for a four month old, you

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    know, just all these things that you build on what you

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    know, as a nurse to become an NP and that just further

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    invigorates me.

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    But back to the question about med titration, I think

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    I think the biggest thing people have is fear, fear of

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    I'm going to do something horrible, or I'm not like

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    I'm going to harm them, but they're going to go

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    home.

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    Yeah.

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    Re-admitted or yeah.

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    Right.

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    All of this.

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    So I have kind of, don't be afraid is the first

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    thing because believe it or not, especially in

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    the context of things like heart failure, you are

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    not going to harm them like, oh, they don't have

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    a blood pressure cuff at home or I can't teach

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    them how to take their pulse.

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    But the bottom line is, if you know the

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    pharmacokinetics and dynamics of the meds,

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    you're golden.

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    So let's just start with beta blockers, right?

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    So I was going to say a lot of these, a lot of

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    people listening could be students and new

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    grads and like experience, like it's a range.

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    So feel free to like start at like square

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    square one, if you want to write like wherever

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    you want to start.

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    00:09:38.090 --> 00:09:38.150

    Yeah.

    217

    00:09:38.170 --> 00:09:40.850

    So, so I will just say my focus from a

    218

    00:09:40.850 --> 00:09:43.470

    medication titration standpoint for a patient

    219

    00:09:43.470 --> 00:09:46.570

    that has heart failure with reduced EF, right?

    220

    00:09:46.570 --> 00:09:49.430

    Less than or equal to 40% that we used to

    221

    00:09:49.430 --> 00:09:53.090

    call systolic heart failure is really about

    222

    00:09:53.090 --> 00:09:55.470

    getting them on their four pillars of therapy.

    223

    00:09:55.710 --> 00:09:56.070

    Okay.

    224

    00:09:56.070 --> 00:09:58.170

    And we'll talk a little bit about preserved

    225

    00:09:58.170 --> 00:10:01.030

    ejection fraction, but the point is

    226

    00:10:01.030 --> 00:10:04.450

    patients live longer and stay out of the

    227

    00:10:04.450 --> 00:10:06.750

    hospital if we can get them even on low

    228

    00:10:06.750 --> 00:10:09.030

    doses of those evidence-based medicines.

    229

    00:10:09.670 --> 00:10:12.690

    So I tend to think in classes, right?

    230

    00:10:12.690 --> 00:10:15.170

    So we've got beta blockers, we've got

    231

    00:10:15.170 --> 00:10:18.770

    the ACE inhibitors, ACE, ARB, ARNI,

    232

    00:10:19.030 --> 00:10:21.830

    angiotensin, nepolysin inhibitors, and

    233

    00:10:21.830 --> 00:10:24.490

    then we've got mineralocorticoid receptor

    234

    00:10:24.490 --> 00:10:26.590

    antagonists, basically our potassium

    235

    00:10:26.590 --> 00:10:28.290

    sparing diuretics, right?

    236

    00:10:28.730 --> 00:10:30.550

    And then SGLT2 inhibitors.

    237

    00:10:31.550 --> 00:10:33.910

    So you look at all of this, how am I

    238

    00:10:33.910 --> 00:10:35.690

    going to get somebody on four medicines

    239

    00:10:35.690 --> 00:10:37.190

    and oh my gosh, how are they going to

    240

    00:10:37.190 --> 00:10:37.690

    afford it?

    241

    00:10:37.690 --> 00:10:39.970

    And that's a lot, but wait a second.

    242

    00:10:40.450 --> 00:10:42.190

    It used to be we'd start one at a

    243

    00:10:42.190 --> 00:10:43.230

    time and go live.

    244

    00:10:43.590 --> 00:10:46.010

    The data shows us that even starting

    245

    00:10:46.010 --> 00:10:49.430

    two or even all four, because average

    246

    00:10:49.430 --> 00:10:51.950

    heart failure hospital stay is four to

    247

    00:10:51.950 --> 00:10:52.830

    seven days.

    248

    00:10:52.830 --> 00:10:54.670

    Well, in that seven days, you can get

    249

    00:10:54.670 --> 00:10:57.110

    those meds, but think about what

    250

    00:10:57.110 --> 00:10:58.190

    you're doing, right?

    251

    00:10:59.430 --> 00:11:01.130

    So example, someone comes in, they

    252

    00:11:01.130 --> 00:11:02.990

    have a history of hypertension and

    253

    00:11:02.990 --> 00:11:04.930

    I'm deciding to start them on an

    254

    00:11:04.930 --> 00:11:06.750

    evidence-based beta blocker, right?

    255

    00:11:07.030 --> 00:11:09.150

    Am I going to pick Carvetilol that

    256

    00:11:09.150 --> 00:11:11.690

    has alpha and beta properties, which

    257

    00:11:11.690 --> 00:11:13.890

    will lower blood pressure, or am I

    258

    00:11:13.890 --> 00:11:16.150

    going to pick the topralol, succinate?

    259

    00:11:16.470 --> 00:11:17.910

    I'm going to pick Carvetilol.

    260

    00:11:18.070 --> 00:11:20.570

    It's twice a day, but now it's

    261

    00:11:20.570 --> 00:11:21.750

    generic, right?

    262

    00:11:21.750 --> 00:11:23.650

    But I can get more bang for my buck.

    263

    00:11:24.430 --> 00:11:25.570

    And fast forward, that's how you

    264

    00:11:25.570 --> 00:11:26.470

    explain it to the patient.

    265

    00:11:27.270 --> 00:11:27.730

    Oh, Ms.

    266

    00:11:27.930 --> 00:11:29.330

    Rohr, I'm going to start you on

    267

    00:11:29.330 --> 00:11:30.450

    a medicine that's going to treat

    268

    00:11:30.450 --> 00:11:31.930

    your heart failure and your high

    269

    00:11:31.930 --> 00:11:32.610

    blood pressure.

    270

    00:11:33.150 --> 00:11:33.170

    Really?

    271

    00:11:34.090 --> 00:11:34.370

    Nice.

    272

    00:11:34.570 --> 00:11:37.010

    I may take away a medicine like a

    273

    00:11:37.010 --> 00:11:38.490

    calcium channel blockers, like

    274

    00:11:38.490 --> 00:11:39.490

    imodipine, right?

    275

    00:11:39.490 --> 00:11:42.510

    So then you've got negotiation and

    276

    00:11:42.510 --> 00:11:43.490

    shared decision-making.

    277

    00:11:44.230 --> 00:11:45.770

    Mitch just took away a medicine,

    278

    00:11:46.030 --> 00:11:46.070

    right?

    279

    00:11:46.070 --> 00:11:46.530

    Totally.

    280

    00:11:47.590 --> 00:11:49.310

    And twice a day, most people can

    281

    00:11:49.310 --> 00:11:51.190

    do, it's the TID ones and the

    282

    00:11:51.190 --> 00:11:51.510

    QID.

    283

    00:11:51.770 --> 00:11:52.830

    I'm like, oh, for gosh sakes,

    284

    00:11:52.830 --> 00:11:53.630

    why do we?

    285

    00:11:54.450 --> 00:11:56.170

    So that's just like one

    286

    00:11:56.170 --> 00:11:57.370

    decision point, right?

    287

    00:11:58.250 --> 00:12:00.010

    Just remember it's metoprolol

    288

    00:12:00.010 --> 00:12:01.610

    succinate, like the long-acting

    289

    00:12:01.610 --> 00:12:02.750

    one we should be using.

    290

    00:12:03.410 --> 00:12:04.850

    And that gets into, so I start

    291

    00:12:04.850 --> 00:12:06.170

    them on an ACE inhibitor and

    292

    00:12:06.170 --> 00:12:07.110

    the blood pressure drops.

    293

    00:12:07.770 --> 00:12:08.790

    Oh my gosh.

    294

    00:12:08.790 --> 00:12:10.390

    But I've had them on a beta

    295

    00:12:10.390 --> 00:12:10.930

    blocker too.

    296

    00:12:10.990 --> 00:12:11.830

    What do I do?

    297

    00:12:12.250 --> 00:12:13.390

    What do you do in that

    298

    00:12:13.390 --> 00:12:13.930

    situation?

    299

    00:12:14.130 --> 00:12:15.130

    Oh man.

    300

    00:12:18.480 --> 00:12:19.700

    I'll give you an easy thing.

    301

    00:12:19.820 --> 00:12:20.560

    Do you ever split your meds?

    302

    00:12:20.560 --> 00:12:21.860

    There's so many options to go.

    303

    00:12:21.940 --> 00:12:22.240

    Go ahead.

    304

    00:12:22.420 --> 00:12:24.060

    But here's an easy peasy one.

    305

    00:12:24.120 --> 00:12:25.120

    This is where I go.

    306

    00:12:25.400 --> 00:12:26.360

    Take one in the morning and

    307

    00:12:26.360 --> 00:12:26.860

    one at night.

    308

    00:12:26.940 --> 00:12:27.980

    They're both once a day.

    309

    00:12:30.060 --> 00:12:30.620

    With carbidolol?

    310

    00:12:30.720 --> 00:12:31.820

    So if it was carbidolol, you

    311

    00:12:31.820 --> 00:12:31.880

    would just...

    312

    00:12:31.880 --> 00:12:33.040

    No, not carbidolol.

    313

    00:12:33.140 --> 00:12:35.480

    So that's, or with carbidolol,

    314

    00:12:35.540 --> 00:12:37.380

    if they're on, say, succubitrol

    315

    00:12:37.380 --> 00:12:38.680

    valsartan, I'm not going to

    316

    00:12:38.680 --> 00:12:40.320

    talk brand names here, but if

    317

    00:12:40.320 --> 00:12:42.240

    they're on like an ACE, ARNI,

    318

    00:12:42.280 --> 00:12:44.280

    or ARB, that's twice a day, I

    319

    00:12:44.280 --> 00:12:47.280

    say, take it at breakfast and

    320

    00:12:47.280 --> 00:12:48.960

    at dinner, and then take your

    321

    00:12:48.960 --> 00:12:50.800

    carbidolol at lunch and at

    322

    00:12:50.800 --> 00:12:51.160

    bedtime.

    323

    00:12:52.220 --> 00:12:53.180

    That's interesting.

    324

    00:12:53.640 --> 00:12:53.940

    Right?

    325

    00:12:53.940 --> 00:12:54.340

    Cool.

    326

    00:12:54.520 --> 00:12:54.720

    Yeah.

    327

    00:12:54.780 --> 00:12:56.700

    We've gotten all the doses in.

    328

    00:12:57.600 --> 00:12:58.640

    Now that's if they're going

    329

    00:12:58.640 --> 00:12:59.380

    to remember that.

    330

    00:12:59.580 --> 00:13:00.440

    We've got to think about what

    331

    00:13:00.440 --> 00:13:01.780

    kind of work they do, or

    332

    00:13:01.780 --> 00:13:03.300

    they can remember to take it.

    333

    00:13:03.360 --> 00:13:03.840

    Totally.

    334

    00:13:03.840 --> 00:13:05.140

    So if they're not going to

    335

    00:13:05.140 --> 00:13:06.900

    remember a twice a day med,

    336

    00:13:07.720 --> 00:13:09.340

    I just put them on once a

    337

    00:13:09.340 --> 00:13:11.340

    day, even for the, you know,

    338

    00:13:11.340 --> 00:13:13.220

    supposedly succubitrol valsartan

    339

    00:13:13.220 --> 00:13:14.880

    has a better efficacy than

    340

    00:13:14.880 --> 00:13:17.140

    maybe gramapro, right?

    341

    00:13:17.220 --> 00:13:19.380

    Like ACE or low sartan.

    342

    00:13:20.300 --> 00:13:21.780

    But if I know they're not

    343

    00:13:21.780 --> 00:13:22.820

    going to take it twice a

    344

    00:13:22.820 --> 00:13:24.120

    day, I'm still, I'm just

    345

    00:13:24.120 --> 00:13:25.900

    going to keep them on the

    346

    00:13:25.900 --> 00:13:26.620

    once a day.

    347

    00:13:26.760 --> 00:13:27.180

    Totally.

    348

    00:13:27.360 --> 00:13:28.280

    And can you say, can you

    349

    00:13:28.280 --> 00:13:29.080

    say a little bit more about

    350

    00:13:29.080 --> 00:13:30.740

    the succubitrol valsartan?

    351

    00:13:30.900 --> 00:13:31.320

    Sure.

    352

    00:13:31.340 --> 00:13:32.720

    So that's, yeah.

    353

    00:13:32.920 --> 00:13:34.760

    So, you know, a brand name,

    354

    00:13:34.760 --> 00:13:35.900

    I'll just say brand name is

    355

    00:13:35.900 --> 00:13:38.180

    Entresto, and it really has

    356

    00:13:38.180 --> 00:13:40.360

    been shown to reduce

    357

    00:13:41.100 --> 00:13:42.280

    hospitalizations, but more

    358

    00:13:42.280 --> 00:13:43.900

    important, the reduction in

    359

    00:13:43.900 --> 00:13:45.560

    symptoms and mortality has

    360

    00:13:45.560 --> 00:13:46.500

    been profound.

    361

    00:13:47.960 --> 00:13:48.720

    So, and this is the

    362

    00:13:48.720 --> 00:13:49.400

    ARNI, correct?

    363

    00:13:49.560 --> 00:13:50.960

    This is an ARNI, right?

    364

    00:13:50.980 --> 00:13:52.100

    So it's inhibiting that

    365

    00:13:52.100 --> 00:13:54.320

    nephrolicin that really is

    366

    00:13:54.320 --> 00:13:55.900

    detrimental in heart failure.

    367

    00:13:56.480 --> 00:13:56.560

    Yeah.

    368

    00:13:56.560 --> 00:13:58.780

    Unfortunately, it's still so

    369

    00:13:58.780 --> 00:14:00.600

    cost prohibitive in some

    370

    00:14:00.600 --> 00:14:02.680

    formularies, but the patient

    371

    00:14:02.680 --> 00:14:05.100

    assistance programs, I'm

    372

    00:14:05.100 --> 00:14:06.720

    fortunate we have APPs in

    373

    00:14:06.720 --> 00:14:08.340

    the hospital, PAs, NMPs,

    374

    00:14:08.580 --> 00:14:09.580

    starting those forms.

    375

    00:14:09.820 --> 00:14:11.200

    Yes, while they're in the

    376

    00:14:11.200 --> 00:14:11.400

    hospital.

    377

    00:14:11.880 --> 00:14:12.940

    outpatient, we're like,

    378

    00:14:13.200 --> 00:14:14.240

    oh, we can follow up,

    379

    00:14:14.280 --> 00:14:15.260

    which is wonderful.

    380

    00:14:15.900 --> 00:14:16.000

    Right.

    381

    00:14:16.560 --> 00:14:18.020

    And that's a big part.

    382

    00:14:18.680 --> 00:14:20.680

    But, but from an initiation

    383

    00:14:20.680 --> 00:14:22.580

    standpoint, I think about,

    384

    00:14:22.580 --> 00:14:23.680

    you know, even if they

    385

    00:14:23.680 --> 00:14:24.480

    started two in the

    386

    00:14:24.480 --> 00:14:25.580

    hospital, so maybe they

    387

    00:14:25.580 --> 00:14:28.200

    started an ARNI and

    388

    00:14:30.260 --> 00:14:31.740

    SGLT2 inhibitor, like

    389

    00:14:31.740 --> 00:14:32.760

    mpagliflozin or

    390

    00:14:32.760 --> 00:14:34.020

    dupagliflozin, another

    391

    00:14:34.020 --> 00:14:35.780

    one shown to reduce

    392

    00:14:36.380 --> 00:14:36.860

    hospitalizations.

    393

    00:14:37.600 --> 00:14:38.680

    You can then, when they

    394

    00:14:38.680 --> 00:14:40.740

    come outpatient, check

    395

    00:14:40.740 --> 00:14:41.740

    labs, right?

    396

    00:14:41.740 --> 00:14:43.820

    And start the potassium

    397

    00:14:43.820 --> 00:14:45.100

    spearing diuretic, the

    398

    00:14:45.100 --> 00:14:46.240

    spironolactone or a

    399

    00:14:46.240 --> 00:14:47.540

    pleurinome, as well as

    400

    00:14:47.540 --> 00:14:48.920

    a beta blocker.

    401

    00:14:50.040 --> 00:14:51.000

    Now I want to back up

    402

    00:14:51.000 --> 00:14:51.340

    a minute.

    403

    00:14:51.720 --> 00:14:53.060

    And so we've talked about

    404

    00:14:53.060 --> 00:14:54.660

    ARNI's and really the

    405

    00:14:54.660 --> 00:14:54.980

    benefit.

    406

    00:14:55.000 --> 00:14:55.880

    So that's your kind of

    407

    00:14:55.880 --> 00:14:57.240

    gold standard, but again,

    408

    00:14:57.560 --> 00:14:59.000

    ACEs and ARBs, if you

    409

    00:14:59.000 --> 00:15:00.120

    can get them on there and

    410

    00:15:00.120 --> 00:15:01.120

    their potassium stays

    411

    00:15:01.120 --> 00:15:02.620

    stable, then you can go

    412

    00:15:02.620 --> 00:15:03.360

    ahead and add that

    413

    00:15:03.360 --> 00:15:04.240

    potassium spearing

    414

    00:15:04.240 --> 00:15:05.060

    diuretic.

    415

    00:15:06.280 --> 00:15:08.040

    But SGLT2 inhibitors,

    416

    00:15:08.540 --> 00:15:09.540

    the cool thing about

    417

    00:15:09.540 --> 00:15:10.660

    them is they

    418

    00:15:10.660 --> 00:15:12.320

    diurese and you can

    419

    00:15:12.320 --> 00:15:14.020

    tell folks that you're

    420

    00:15:14.020 --> 00:15:15.540

    going to be urinating

    421

    00:15:15.540 --> 00:15:16.660

    out sugar or you're

    422

    00:15:16.660 --> 00:15:17.680

    going to pee out sugar.

    423

    00:15:18.060 --> 00:15:18.840

    We might be able to

    424

    00:15:18.840 --> 00:15:19.640

    back off on your

    425

    00:15:19.640 --> 00:15:20.260

    fluid pill.

    426

    00:15:21.320 --> 00:15:22.760

    That's another benefit.

    427

    00:15:23.120 --> 00:15:24.500

    Renal protection, right?

    428

    00:15:24.780 --> 00:15:25.900

    Preserving the kidneys,

    429

    00:15:26.900 --> 00:15:27.980

    ACEs, ARBs, all

    430

    00:15:27.980 --> 00:15:29.060

    protect the kidneys,

    431

    00:15:29.100 --> 00:15:30.620

    even without diabetes.

    432

    00:15:31.220 --> 00:15:31.960

    But gosh, if I can

    433

    00:15:31.960 --> 00:15:32.700

    get you off a

    434

    00:15:32.700 --> 00:15:34.340

    diuretic or a

    435

    00:15:34.340 --> 00:15:34.940

    lower dose,

    436

    00:15:35.780 --> 00:15:37.240

    less, you know, another

    437

    00:15:37.240 --> 00:15:38.140

    win, right?

    438

    00:15:38.860 --> 00:15:39.060

    Right.

    439

    00:15:39.180 --> 00:15:40.680

    Less meds, but less

    440

    00:15:40.680 --> 00:15:42.720

    disruption in lifestyle.

    441

    00:15:42.860 --> 00:15:43.280

    Yep.

    442

    00:15:43.960 --> 00:15:45.620

    Um, so all of that,

    443

    00:15:45.820 --> 00:15:47.480

    I think so often when

    444

    00:15:47.480 --> 00:15:48.980

    I start like, uh,

    445

    00:15:49.040 --> 00:15:50.240

    impagliflozin, for

    446

    00:15:50.240 --> 00:15:52.420

    example, um, I will

    447

    00:15:52.420 --> 00:15:53.260

    cut their diuretic

    448

    00:15:53.260 --> 00:15:53.980

    dose in half.

    449

    00:15:54.140 --> 00:15:55.240

    Now, sometimes people

    450

    00:15:55.240 --> 00:15:56.460

    are like, don't do

    451

    00:15:56.460 --> 00:15:57.000

    that.

    452

    00:15:57.240 --> 00:15:58.800

    Like, remember diuretics

    453

    00:15:58.800 --> 00:16:00.240

    are just palliative.

    454

    00:16:00.240 --> 00:16:01.280

    They're just treating

    455

    00:16:01.280 --> 00:16:02.180

    your symptoms.

    456

    00:16:02.680 --> 00:16:04.240

    So there's no

    457

    00:16:04.240 --> 00:16:05.100

    mortality benefit.

    458

    00:16:05.100 --> 00:16:06.240

    You'd rather be on

    459

    00:16:06.240 --> 00:16:07.720

    this impagliflozin,

    460

    00:16:07.920 --> 00:16:09.320

    dupagliflozin, even now

    461

    00:16:09.320 --> 00:16:10.980

    sotagliflozin, to

    462

    00:16:10.980 --> 00:16:12.400

    help you improve

    463

    00:16:12.400 --> 00:16:13.100

    your mortality.

    464

    00:16:13.380 --> 00:16:13.820

    Yes.

    465

    00:16:14.120 --> 00:16:14.260

    Yep.

    466

    00:16:14.540 --> 00:16:14.740

    Right.

    467

    00:16:14.940 --> 00:16:15.280

    Totally.

    468

    00:16:15.880 --> 00:16:17.500

    Do you know that now,

    469

    00:16:18.200 --> 00:16:19.700

    um, it's still one

    470

    00:16:19.700 --> 00:16:20.860

    in five, the mortality

    471

    00:16:20.860 --> 00:16:22.720

    is 50% at five years

    472

    00:16:22.720 --> 00:16:23.780

    with you have a

    473

    00:16:23.780 --> 00:16:24.520

    diagnosis of heart

    474

    00:16:24.520 --> 00:16:24.960

    failure.

    475

    00:16:24.960 --> 00:16:25.480

    Wow.

    476

    00:16:25.800 --> 00:16:26.860

    It has been that day

    477

    00:16:26.860 --> 00:16:27.940

    since I, way since

    478

    00:16:27.940 --> 00:16:29.540

    I started in 1999.

    479

    00:16:29.940 --> 00:16:31.040

    We have not moved

    480

    00:16:31.040 --> 00:16:31.980

    the needle enough.

    481

    00:16:32.500 --> 00:16:32.780

    Yeah.

    482

    00:16:33.140 --> 00:16:33.700

    Yeah.

    483

    00:16:33.960 --> 00:16:34.640

    Oh man.

    484

    00:16:35.300 --> 00:16:35.740

    Yeah.

    485

    00:16:36.000 --> 00:16:36.900

    So I guess, I

    486

    00:16:36.900 --> 00:16:37.580

    guess in terms of the

    487

    00:16:37.580 --> 00:16:38.420

    titration, I guess I'm

    488

    00:16:38.420 --> 00:16:39.480

    thinking about students

    489

    00:16:39.480 --> 00:16:40.140

    and thinking about new

    490

    00:16:40.700 --> 00:16:42.180

    grads and I'm thinking

    491

    00:16:42.180 --> 00:16:43.060

    about some scenarios.

    492

    00:16:43.060 --> 00:16:45.760

    So I, um, yeah,

    493

    00:16:45.760 --> 00:16:46.640

    like what, I guess,

    494

    00:16:46.640 --> 00:16:47.480

    do you have any idea

    495

    00:16:47.480 --> 00:16:48.460

    of like common scenarios

    496

    00:16:48.460 --> 00:16:49.260

    that you see that

    497

    00:16:49.260 --> 00:16:50.140

    like people are

    498

    00:16:50.140 --> 00:16:50.740

    calling about?

    499

    00:16:50.780 --> 00:16:51.960

    Like, is it, so my

    500

    00:16:51.960 --> 00:16:52.660

    background is in

    501

    00:16:52.660 --> 00:16:53.180

    federally qualified

    502

    00:16:53.180 --> 00:16:53.800

    health centers.

    503

    00:16:53.800 --> 00:16:55.200

    And so it wouldn't

    504

    00:16:55.200 --> 00:16:56.560

    have the most kind

    505

    00:16:56.560 --> 00:16:57.300

    of like novel

    506

    00:16:57.300 --> 00:16:58.360

    medications because of

    507

    00:16:58.360 --> 00:16:59.420

    cost being cost

    508

    00:16:59.420 --> 00:16:59.860

    prohibitive.

    509

    00:16:59.880 --> 00:17:00.940

    And so, and we also

    510

    00:17:00.940 --> 00:17:01.760

    have the situation of

    511

    00:17:01.760 --> 00:17:02.600

    patients who weren't

    512

    00:17:02.600 --> 00:17:03.600

    able to go to

    513

    00:17:03.600 --> 00:17:04.420

    cardiology for a long

    514

    00:17:04.420 --> 00:17:05.760

    time or like, just

    515

    00:17:05.760 --> 00:17:06.440

    missed their appointments

    516

    00:17:06.440 --> 00:17:07.020

    because they ran out

    517

    00:17:07.020 --> 00:17:07.720

    of insurance, like

    518

    00:17:07.720 --> 00:17:08.400

    things like that.

    519

    00:17:08.599 --> 00:17:09.579

    And so, or don't

    520

    00:17:09.579 --> 00:17:10.760

    have transportation.

    521

    00:17:11.119 --> 00:17:11.520

    Yeah.

    522

    00:17:11.760 --> 00:17:13.660

    And so I think totally.

    523

    00:17:13.880 --> 00:17:14.420

    And I feel, so I

    524

    00:17:14.420 --> 00:17:15.319

    feel like the, there's

    525

    00:17:15.319 --> 00:17:16.160

    so many pieces, so

    526

    00:17:16.160 --> 00:17:16.819

    many things we could

    527

    00:17:16.819 --> 00:17:17.900

    touch on with that

    528

    00:17:17.900 --> 00:17:18.640

    scenario, but I guess

    529

    00:17:18.640 --> 00:17:19.319

    when it comes to the

    530

    00:17:19.319 --> 00:17:21.420

    medications, so just

    531

    00:17:21.420 --> 00:17:22.260

    to like, kind of

    532

    00:17:22.260 --> 00:17:23.200

    like ground reorient,

    533

    00:17:23.240 --> 00:17:24.160

    like what our goal

    534

    00:17:24.160 --> 00:17:24.819

    for heart failure

    535

    00:17:24.819 --> 00:17:25.880

    patients is that they're

    536

    00:17:25.880 --> 00:17:26.640

    on those guideline

    537

    00:17:26.640 --> 00:17:27.740

    directed medical

    538

    00:17:27.740 --> 00:17:28.840

    treatments, GDMT,

    539

    00:17:28.860 --> 00:17:29.340

    which is those

    540

    00:17:29.340 --> 00:17:29.940

    classes that you

    541

    00:17:29.940 --> 00:17:31.140

    talked about, um,

    542

    00:17:31.140 --> 00:17:32.060

    which we, I touched

    543

    00:17:32.060 --> 00:17:32.840

    on in the, in that

    544

    00:17:32.840 --> 00:17:33.380

    other heart failure

    545

    00:17:33.380 --> 00:17:34.520

    episode, but like the

    546

    00:17:34.520 --> 00:17:35.600

    goal is to get them

    547

    00:17:35.600 --> 00:17:36.460

    on those medicines

    548

    00:17:36.460 --> 00:17:38.680

    at the goal doses.

    549

    00:17:39.160 --> 00:17:39.640

    Correct.

    550

    00:17:40.120 --> 00:17:40.660

    Based on like

    551

    00:17:40.660 --> 00:17:41.960

    the research studies.

    552

    00:17:42.660 --> 00:17:43.960

    Except that recently

    553

    00:17:43.960 --> 00:17:45.180

    I read and I'm

    554

    00:17:45.180 --> 00:17:45.840

    going to read this

    555

    00:17:45.840 --> 00:17:46.740

    cause I wrote better

    556

    00:17:46.740 --> 00:17:47.540

    to have the patient

    557

    00:17:47.540 --> 00:17:48.880

    on low doses of all

    558

    00:17:48.880 --> 00:17:50.360

    four rather than

    559

    00:17:50.360 --> 00:17:52.560

    fewer meds at the

    560

    00:17:52.560 --> 00:17:53.360

    target dose.

    561

    00:17:53.500 --> 00:17:54.300

    That's so interesting.

    562

    00:17:54.380 --> 00:17:55.740

    So, so the script

    563

    00:17:55.740 --> 00:17:56.840

    has flipped a little.

    564

    00:17:56.960 --> 00:17:58.240

    It used to be sequential

    565

    00:17:58.240 --> 00:17:59.780

    adding, get them to

    566

    00:17:59.780 --> 00:18:00.920

    don't add the next

    567

    00:18:00.920 --> 00:18:01.540

    till you're really

    568

    00:18:01.540 --> 00:18:02.140

    titrated up.

    569

    00:18:02.300 --> 00:18:03.220

    Now it's like, get them

    570

    00:18:03.220 --> 00:18:04.800

    on all four, believe

    571

    00:18:04.800 --> 00:18:06.200

    it or not, titrate

    572

    00:18:06.200 --> 00:18:08.140

    every one to two weeks.

    573

    00:18:08.440 --> 00:18:08.840

    Wow.

    574

    00:18:09.060 --> 00:18:10.640

    Based on really fast.

    575

    00:18:10.960 --> 00:18:11.320

    Wow.

    576

    00:18:11.320 --> 00:18:12.220

    Based on, and we, yeah,

    577

    00:18:12.220 --> 00:18:12.800

    what are you, what are

    578

    00:18:12.800 --> 00:18:13.320

    you looking at

    579

    00:18:13.320 --> 00:18:13.820

    when you're titrated?

    580

    00:18:13.820 --> 00:18:14.720

    Is this outpatient or is

    581

    00:18:14.720 --> 00:18:15.580

    this in this sounds

    582

    00:18:15.580 --> 00:18:16.340

    like it's outpatient?

    583

    00:18:16.460 --> 00:18:16.720

    Okay.

    584

    00:18:16.960 --> 00:18:17.920

    Absolutely outpatient.

    585

    00:18:18.220 --> 00:18:20.060

    And we have, um, like

    586

    00:18:20.060 --> 00:18:21.340

    I might see you in

    587

    00:18:21.340 --> 00:18:22.820

    clinic and bump your,

    588

    00:18:23.180 --> 00:18:23.920

    let's just do beta

    589

    00:18:23.920 --> 00:18:24.640

    blocker, right?

    590

    00:18:24.740 --> 00:18:24.940

    You have bumped

    591

    00:18:24.940 --> 00:18:26.160

    your beta blocker up.

    592

    00:18:26.200 --> 00:18:26.600

    Yeah.

    593

    00:18:26.760 --> 00:18:28.100

    And I might have an

    594

    00:18:28.100 --> 00:18:29.160

    a pharmacist or a

    595

    00:18:29.160 --> 00:18:29.920

    nurse call you in a

    596

    00:18:29.920 --> 00:18:30.660

    week and have you

    597

    00:18:30.660 --> 00:18:31.460

    go up again.

    598

    00:18:32.600 --> 00:18:32.900

    Based on your

    599

    00:18:32.900 --> 00:18:33.400

    blood pressure and

    600

    00:18:33.400 --> 00:18:34.080

    how they're feeling.

    601

    00:18:34.240 --> 00:18:35.280

    If any orthostasis

    602

    00:18:35.280 --> 00:18:36.040

    or dizziness, things

    603

    00:18:36.040 --> 00:18:36.580

    like that.

    604

    00:18:37.060 --> 00:18:37.700

    So symptoms are

    605

    00:18:37.700 --> 00:18:38.440

    often the driver

    606

    00:18:38.440 --> 00:18:39.460

    because I can't tell

    607

    00:18:39.460 --> 00:18:40.480

    you how many times

    608

    00:18:40.480 --> 00:18:41.480

    we get, we are

    609

    00:18:41.480 --> 00:18:42.620

    the ones as providers

    610

    00:18:42.620 --> 00:18:43.700

    that get hung up

    611

    00:18:43.700 --> 00:18:44.520

    on having, well,

    612

    00:18:44.540 --> 00:18:44.960

    what their blood

    613

    00:18:44.960 --> 00:18:45.560

    pressure do, what

    614

    00:18:45.560 --> 00:18:46.140

    their heart rate.

    615

    00:18:46.340 --> 00:18:46.400

    Yep.

    616

    00:18:46.640 --> 00:18:46.900

    Yep.

    617

    00:18:47.020 --> 00:18:48.340

    If they're in your

    618

    00:18:48.340 --> 00:18:49.520

    clinic today with

    619

    00:18:49.520 --> 00:18:50.780

    a resting heart rate

    620

    00:18:50.780 --> 00:18:52.060

    in the eighties and

    621

    00:18:52.060 --> 00:18:53.300

    your goal is to

    622

    00:18:53.300 --> 00:18:54.360

    have a resting heart

    623

    00:18:54.360 --> 00:18:55.900

    rate in the seventies,

    624

    00:18:55.900 --> 00:18:56.340

    right?

    625

    00:18:56.460 --> 00:18:57.380

    Because when they're

    626

    00:18:57.380 --> 00:18:57.960

    active, it's going to

    627

    00:18:57.960 --> 00:18:58.440

    go up.

    628

    00:18:59.360 --> 00:19:00.380

    You can feel free

    629

    00:19:00.380 --> 00:19:01.280

    to start them on

    630

    00:19:01.280 --> 00:19:02.500

    25 on the Topra

    631

    00:19:02.500 --> 00:19:04.300

    call, succinate and

    632

    00:19:04.300 --> 00:19:06.040

    then titrated at that

    633

    00:19:06.040 --> 00:19:07.900

    visit to 50 and

    634

    00:19:07.900 --> 00:19:08.680

    then a phone call

    635

    00:19:08.680 --> 00:19:10.600

    later to a hundred

    636

    00:19:11.180 --> 00:19:11.920

    as long as they're

    637

    00:19:11.920 --> 00:19:12.760

    asymptomatic.

    638

    00:19:12.820 --> 00:19:13.600

    So it's more

    639

    00:19:13.600 --> 00:19:14.580

    important to catch

    640

    00:19:14.580 --> 00:19:15.640

    that orthostatic

    641

    00:19:15.640 --> 00:19:17.000

    hypotension, like

    642

    00:19:17.520 --> 00:19:18.460

    in the South,

    643

    00:19:18.600 --> 00:19:19.200

    we call it

    644

    00:19:19.200 --> 00:19:19.720

    Swimmy headed.

    645

    00:19:20.100 --> 00:19:20.800

    So do you get all

    646

    00:19:20.800 --> 00:19:21.800

    Swimmy headed when

    647

    00:19:21.800 --> 00:19:23.060

    you stand up from

    648

    00:19:23.060 --> 00:19:23.620

    the chair?

    649

    00:19:23.700 --> 00:19:24.700

    Isn't that cute?

    650

    00:19:24.860 --> 00:19:25.860

    It's really

    651

    00:19:25.860 --> 00:19:26.420

    descriptive.

    652

    00:19:26.680 --> 00:19:26.940

    Yeah.

    653

    00:19:26.940 --> 00:19:27.440

    You could say

    654

    00:19:27.440 --> 00:19:28.320

    lightheaded, dizzy,

    655

    00:19:28.520 --> 00:19:29.040

    but really.

    656

    00:19:29.060 --> 00:19:29.580

    Yeah.

    657

    00:19:29.700 --> 00:19:30.140

    Swimmy headed.

    658

    00:19:30.540 --> 00:19:31.320

    Stand up, you

    659

    00:19:31.320 --> 00:19:32.300

    get your head feels

    660

    00:19:32.500 --> 00:19:33.860

    I'm not going to titrate

    661

    00:19:33.860 --> 00:19:34.480

    or I'm going to

    662

    00:19:34.480 --> 00:19:35.480

    split your dose

    663

    00:19:35.480 --> 00:19:35.880

    right.

    664

    00:19:35.880 --> 00:19:36.580

    Morning and night,

    665

    00:19:36.660 --> 00:19:37.260

    you know,

    666

    00:19:37.280 --> 00:19:37.840

    alternate it

    667

    00:19:37.840 --> 00:19:38.420

    with the other

    668

    00:19:38.420 --> 00:19:39.760

    therapies or

    669

    00:19:39.760 --> 00:19:41.100

    de-prescribed that

    670

    00:19:41.100 --> 00:19:41.920

    calcium channel

    671

    00:19:41.920 --> 00:19:42.740

    blocker or

    672

    00:19:42.740 --> 00:19:43.540

    something else

    673

    00:19:43.540 --> 00:19:44.400

    that might make

    674

    00:19:44.400 --> 00:19:45.560

    you dizzy.

    675

    00:19:46.340 --> 00:19:46.840

    But really,

    676

    00:19:47.040 --> 00:19:47.800

    as opposed to

    677

    00:19:47.800 --> 00:19:49.000

    over several months,

    678

    00:19:49.560 --> 00:19:50.200

    the clinical

    679

    00:19:50.200 --> 00:19:50.980

    benefit is to

    680

    00:19:50.980 --> 00:19:51.480

    have you on

    681

    00:19:51.480 --> 00:19:52.100

    all four

    682

    00:19:52.100 --> 00:19:52.620

    medicines,

    683

    00:19:52.640 --> 00:19:53.500

    even within

    684

    00:19:53.500 --> 00:19:54.720

    that first month

    685

    00:19:54.720 --> 00:19:56.040

    with titration

    686

    00:19:56.040 --> 00:19:57.140

    to maximally

    687

    00:19:57.140 --> 00:19:57.640

    tolerated

    688

    00:19:57.640 --> 00:19:58.180

    doses.

    689

    00:19:59.280 --> 00:19:59.720

    Sometimes it's

    690

    00:19:59.720 --> 00:20:00.540

    symptom driven.

    691

    00:20:00.780 --> 00:20:01.400

    Sometimes it's

    692

    00:20:01.400 --> 00:20:01.880

    blood pressure

    693

    00:20:01.880 --> 00:20:02.360

    driven and

    694

    00:20:02.360 --> 00:20:03.220

    a lot of folks do

    695

    00:20:03.220 --> 00:20:03.840

    have a home

    696

    00:20:03.840 --> 00:20:04.740

    blood pressure cuff.

    697

    00:20:05.040 --> 00:20:05.540

    Yeah.

    698

    00:20:05.680 --> 00:20:06.120

    Yeah.

    699

    00:20:06.380 --> 00:20:07.460

    The key for me,

    700

    00:20:07.460 --> 00:20:08.180

    the safety

    701

    00:20:08.180 --> 00:20:08.660

    issue,

    702

    00:20:08.660 --> 00:20:09.740

    and this is my pearl,

    703

    00:20:10.280 --> 00:20:10.880

    is make

    704

    00:20:10.880 --> 00:20:12.180

    sure you check

    705

    00:20:12.760 --> 00:20:13.540

    kidney function

    706

    00:20:13.540 --> 00:20:14.480

    and potassium

    707

    00:20:14.480 --> 00:20:16.120

    a week after

    708

    00:20:16.120 --> 00:20:16.840

    you start

    709

    00:20:16.840 --> 00:20:18.260

    like spironolactone

    710

    00:20:18.260 --> 00:20:19.340

    or clarinone

    711

    00:20:19.340 --> 00:20:20.260

    because that

    712

    00:20:20.260 --> 00:20:21.100

    in combination,

    713

    00:20:21.280 --> 00:20:21.560

    I mean,

    714

    00:20:21.580 --> 00:20:22.320

    it sounds like

    715

    00:20:22.320 --> 00:20:22.960

    best practice,

    716

    00:20:22.960 --> 00:20:24.140

    but I will see

    717

    00:20:24.140 --> 00:20:25.320

    them back in my clinic.

    718

    00:20:25.380 --> 00:20:26.180

    They're two hours

    719

    00:20:26.180 --> 00:20:26.700

    away in their

    720

    00:20:26.700 --> 00:20:27.260

    home clinic.

    721

    00:20:27.580 --> 00:20:28.600

    So what do I do?

    722

    00:20:29.460 --> 00:20:30.400

    I fax an order

    723

    00:20:30.400 --> 00:20:31.300

    or submit an order

    724

    00:20:31.300 --> 00:20:31.940

    to their primary

    725

    00:20:31.940 --> 00:20:32.620

    care provider.

    726

    00:20:32.940 --> 00:20:33.300

    Totally,

    727

    00:20:33.940 --> 00:20:34.360

    And honestly,

    728

    00:20:34.500 --> 00:20:35.200

    like we need,

    729

    00:20:35.340 --> 00:20:36.060

    I feel like I just,

    730

    00:20:36.180 --> 00:20:37.440

    I'm having flashbacks

    731

    00:20:37.440 --> 00:20:38.160

    to being a new grad

    732

    00:20:38.160 --> 00:20:38.520

    and like,

    733

    00:20:38.700 --> 00:20:39.320

    I feel like we need

    734

    00:20:39.320 --> 00:20:39.900

    all the reminders

    735

    00:20:39.900 --> 00:20:40.920

    we can get.

    736

    00:20:41.600 --> 00:20:42.620

    If that's in there,

    737

    00:20:42.660 --> 00:20:42.820

    right?

    738

    00:20:42.880 --> 00:20:43.140

    I'm like,

    739

    00:20:43.140 --> 00:20:43.440

    yeah,

    740

    00:20:43.440 --> 00:20:44.180

    we do want to check

    741

    00:20:44.180 --> 00:20:44.740

    those labs.

    742

    00:20:44.840 --> 00:20:45.180

    Yeah.

    743

    00:20:45.220 --> 00:20:45.720

    And I just,

    744

    00:20:45.840 --> 00:20:46.300

    I do want to,

    745

    00:20:46.300 --> 00:20:47.040

    I do want to pause

    746

    00:20:47.040 --> 00:20:47.400

    and say,

    747

    00:20:47.440 --> 00:20:47.580

    like,

    748

    00:20:47.580 --> 00:20:48.180

    if you're a new

    749

    00:20:48.180 --> 00:20:48.840

    grad listening

    750

    00:20:48.840 --> 00:20:49.780

    and you're like,

    751

    00:20:49.860 --> 00:20:50.160

    wow,

    752

    00:20:50.160 --> 00:20:50.840

    I'm overwhelmed.

    753

    00:20:50.840 --> 00:20:51.860

    Like that is also

    754

    00:20:51.860 --> 00:20:52.880

    normal and fine

    755

    00:20:52.880 --> 00:20:54.180

    because I would actually

    756

    00:20:54.180 --> 00:20:54.920

    recommend you tag

    757

    00:20:54.920 --> 00:20:55.580

    teaming with somebody.

    758

    00:20:55.640 --> 00:20:56.540

    If you have a patient

    759

    00:20:56.540 --> 00:20:57.220

    with heart failure,

    760

    00:20:57.400 --> 00:20:57.920

    needing multiple

    761

    00:20:57.920 --> 00:20:59.000

    medication titrations,

    762

    00:20:59.000 --> 00:21:00.120

    like that's probably not

    763

    00:21:00.120 --> 00:21:01.220

    for a super novice.

    764

    00:21:01.280 --> 00:21:02.180

    Like you can do it,

    765

    00:21:02.180 --> 00:21:03.440

    but like let's run that

    766

    00:21:03.440 --> 00:21:04.260

    by somebody too,

    767

    00:21:04.340 --> 00:21:05.000

    just to like double

    768

    00:21:05.000 --> 00:21:05.960

    check ourselves there.

    769

    00:21:06.340 --> 00:21:06.700

    So.

    770

    00:21:07.300 --> 00:21:08.260

    And I'll be really

    771

    00:21:08.260 --> 00:21:08.680

    transparent.

    772

    00:21:08.800 --> 00:21:09.400

    The guidelines,

    773

    00:21:09.500 --> 00:21:11.080

    like all these updates

    774

    00:21:11.080 --> 00:21:12.540

    and I look for green,

    775

    00:21:12.540 --> 00:21:13.400

    yellow and red.

    776

    00:21:13.580 --> 00:21:13.880

    Yeah.

    777

    00:21:13.880 --> 00:21:15.380

    I actually have at my

    778

    00:21:15.380 --> 00:21:16.220

    work site,

    779

    00:21:16.400 --> 00:21:18.160

    the printed one pager

    780

    00:21:18.160 --> 00:21:19.220

    that says heart

    781

    00:21:19.220 --> 00:21:20.580

    failure with reduced EF.

    782

    00:21:20.860 --> 00:21:21.540

    What's all green?

    783

    00:21:21.560 --> 00:21:22.840

    Should I be thinking about?

    784

    00:21:23.140 --> 00:21:23.520

    Not that I'm going

    785

    00:21:23.520 --> 00:21:24.360

    to do it all today.

    786

    00:21:24.620 --> 00:21:24.920

    Yeah.

    787

    00:21:25.100 --> 00:21:25.880

    What's all,

    788

    00:21:26.020 --> 00:21:26.660

    what's yellow?

    789

    00:21:26.900 --> 00:21:27.880

    What's orange?

    790

    00:21:27.940 --> 00:21:28.320

    Yeah.

    791

    00:21:28.320 --> 00:21:29.420

    Because for half path,

    792

    00:21:29.680 --> 00:21:30.640

    we never had anything

    793

    00:21:30.640 --> 00:21:31.860

    except diuretics.

    794

    00:21:31.940 --> 00:21:32.880

    And now it's like,

    795

    00:21:32.920 --> 00:21:35.100

    Oh, think about SGLT twos.

    796

    00:21:35.320 --> 00:21:36.200

    Well, if I didn't have that

    797

    00:21:36.200 --> 00:21:36.900

    radical little board

    798

    00:21:36.900 --> 00:21:37.660

    next to me.

    799

    00:21:37.860 --> 00:21:38.080

    Totally.

    800

    00:21:38.220 --> 00:21:38.880

    I wouldn't be like,

    801

    00:21:40.420 --> 00:21:42.260

    just treat the comorbidities,

    802

    00:21:42.340 --> 00:21:43.040

    but you know,

    803

    00:21:43.080 --> 00:21:43.500

    on, right?

    804

    00:21:44.320 --> 00:21:45.040

    You know,

    805

    00:21:45.320 --> 00:21:47.380

    so we all need cues

    806

    00:21:47.380 --> 00:21:48.000

    and reminder.

    807

    00:21:48.460 --> 00:21:49.620

    And I mean,

    808

    00:21:49.840 --> 00:21:51.380

    I'm not embarrassed to say

    809

    00:21:51.380 --> 00:21:52.740

    I will go to up to date

    810

    00:21:52.740 --> 00:21:53.680

    in front of the patient.

    811

    00:21:53.940 --> 00:21:54.960

    I heard you in an episode

    812

    00:21:54.960 --> 00:21:55.780

    talking about,

    813

    00:21:55.840 --> 00:21:56.280

    Oh yeah, yeah.

    814

    00:21:56.440 --> 00:21:57.120

    Leaving the room,

    815

    00:21:57.260 --> 00:21:57.680

    go here.

    816

    00:21:57.680 --> 00:21:59.680

    Or go to my clinical guidelines

    817

    00:21:59.680 --> 00:22:01.380

    app and just look at my phone.

    818

    00:22:01.740 --> 00:22:02.320

    We're just checking

    819

    00:22:02.320 --> 00:22:03.540

    a minute to make sure

    820

    00:22:03.540 --> 00:22:04.900

    that I'm not missing anything.

    821

    00:22:05.400 --> 00:22:06.760

    And patients appreciate that.

    822

    00:22:07.120 --> 00:22:07.340

    They do.

    823

    00:22:07.580 --> 00:22:08.060

    They do.

    824

    00:22:08.140 --> 00:22:08.880

    I feel like I had so much

    825

    00:22:08.880 --> 00:22:09.880

    imposter syndrome

    826

    00:22:09.880 --> 00:22:10.420

    as a new grad.

    827

    00:22:10.500 --> 00:22:11.320

    I couldn't handle being

    828

    00:22:11.320 --> 00:22:12.020

    in front of the patient

    829

    00:22:12.020 --> 00:22:12.360

    doing it.

    830

    00:22:12.460 --> 00:22:13.380

    But now, yeah, totally.

    831

    00:22:13.460 --> 00:22:13.880

    Same thing.

    832

    00:22:14.000 --> 00:22:14.320

    I'm just like,

    833

    00:22:14.320 --> 00:22:15.280

    Yeah, we're just just

    834

    00:22:15.280 --> 00:22:16.140

    do some double check-in.

    835

    00:22:16.680 --> 00:22:17.080

    Yeah.

    836

    00:22:17.280 --> 00:22:18.660

    And I'm glad you mentioned

    837

    00:22:18.660 --> 00:22:19.400

    FHA,

    838

    00:22:20.900 --> 00:22:21.780

    federally qualified

    839

    00:22:21.780 --> 00:22:24.100

    health centers, FQHCs.

    840

    00:22:24.480 --> 00:22:26.220

    Because I do think about that

    841

    00:22:26.220 --> 00:22:27.320

    and I keep up to date

    842

    00:22:27.320 --> 00:22:28.760

    what's on their formulary.

    843

    00:22:28.780 --> 00:22:30.240

    So you're going to see,

    844

    00:22:30.240 --> 00:22:31.740

    you know, so-and-so

    845

    00:22:31.740 --> 00:22:34.040

    at the local community

    846

    00:22:34.960 --> 00:22:35.400

    clinic.

    847

    00:22:36.100 --> 00:22:39.220

    OK, I know that these meds

    848

    00:22:39.220 --> 00:22:40.940

    are on that formulary, right?

    849

    00:22:41.040 --> 00:22:41.680

    And I can't,

    850

    00:22:41.720 --> 00:22:42.780

    but I'm going to write a note,

    851

    00:22:42.840 --> 00:22:44.440

    make sure your provider gets it.

    852

    00:22:44.440 --> 00:22:45.220

    They're going to see

    853

    00:22:45.220 --> 00:22:46.380

    what the plan is.

    854

    00:22:46.560 --> 00:22:47.620

    So I try to be as

    855

    00:22:47.620 --> 00:22:49.100

    transparent in my plan,

    856

    00:22:50.820 --> 00:22:51.980

    which I'll give you

    857

    00:22:51.980 --> 00:22:52.760

    my student story.

    858

    00:22:52.920 --> 00:22:54.420

    I have grads that work inpatient

    859

    00:22:54.420 --> 00:22:55.180

    in the hospital.

    860

    00:22:55.540 --> 00:22:56.840

    And all of a sudden

    861

    00:22:56.840 --> 00:22:58.620

    I had a student

    862

    00:22:59.100 --> 00:23:00.560

    dictating their discharge summary

    863

    00:23:00.560 --> 00:23:02.140

    and it would say needs

    864

    00:23:02.140 --> 00:23:03.160

    need to get a basic

    865

    00:23:03.160 --> 00:23:04.000

    metabolic panel,

    866

    00:23:04.040 --> 00:23:04.980

    should titrate this,

    867

    00:23:05.000 --> 00:23:05.560

    should do this.

    868

    00:23:05.580 --> 00:23:06.380

    And they'd say, Dr.

    869

    00:23:06.500 --> 00:23:07.620

    Bowers, I felt terrible

    870

    00:23:07.620 --> 00:23:09.340

    telling you what to do,

    871

    00:23:09.420 --> 00:23:09.940

    knowing you were going

    872

    00:23:09.940 --> 00:23:10.740

    to see them in clinic.

    873

    00:23:10.980 --> 00:23:12.100

    I was like, oh, no,

    874

    00:23:12.340 --> 00:23:13.620

    I would much rather

    875

    00:23:13.620 --> 00:23:15.240

    in a busy clinic.

    876

    00:23:15.240 --> 00:23:15.560

    Yeah.

    877

    00:23:15.620 --> 00:23:17.140

    Have you A, remind me

    878

    00:23:17.140 --> 00:23:18.740

    or B, guide my treatment

    879

    00:23:18.740 --> 00:23:19.680

    so that we're all

    880

    00:23:19.680 --> 00:23:20.920

    part of the same team.

    881

    00:23:21.000 --> 00:23:21.440

    Totally.

    882

    00:23:21.720 --> 00:23:23.020

    So I'm going to say, Liz,

    883

    00:23:23.360 --> 00:23:25.520

    you know, to get follow up labs

    884

    00:23:25.520 --> 00:23:26.880

    at PCP visit

    885

    00:23:26.880 --> 00:23:27.800

    with nurse practitioner

    886

    00:23:27.800 --> 00:23:29.960

    role like that's what I really do.

    887

    00:23:30.380 --> 00:23:31.020

    Yeah, I love it.

    888

    00:23:31.020 --> 00:23:31.920

    I love it when they have a plan.

    889

    00:23:31.920 --> 00:23:32.460

    I'm like, thank you

    890

    00:23:32.460 --> 00:23:33.320

    for telling me what to do

    891

    00:23:34.520 --> 00:23:35.780

    because we're so busy

    892

    00:23:35.780 --> 00:23:37.160

    and so overloaded

    893

    00:23:37.160 --> 00:23:38.820

    that that just kind of guides it.

    894

    00:23:38.820 --> 00:23:40.820

    And it also shows the partnership.

    895

    00:23:41.340 --> 00:23:42.200

    Totally, totally.

    896

    00:23:42.240 --> 00:23:43.080

    And if you think about it,

    897

    00:23:43.080 --> 00:23:45.040

    like at least I do that for myself

    898

    00:23:45.040 --> 00:23:46.360

    when I make my own plan of care,

    899

    00:23:46.420 --> 00:23:47.860

    I'm spelling it out for myself,

    900

    00:23:47.860 --> 00:23:49.080

    but also it's spelling it out

    901

    00:23:49.080 --> 00:23:49.840

    for the next provider.

    902

    00:23:49.880 --> 00:23:51.000

    If I'm not there that day

    903

    00:23:51.000 --> 00:23:52.360

    or or if that person comes in

    904

    00:23:52.360 --> 00:23:53.460

    in between our next follow up,

    905

    00:23:53.520 --> 00:23:54.140

    like they're going to know

    906

    00:23:54.140 --> 00:23:55.380

    what the deal is like they can.

    907

    00:23:55.380 --> 00:23:56.380

    Oh, I can. I'm tracking

    908

    00:23:56.380 --> 00:23:57.720

    based on your HBI and your plan.

    909

    00:23:57.920 --> 00:23:58.700

    Like what the plan?

    910

    00:23:58.900 --> 00:24:00.140

    Yeah, yes, absolutely.

    911

    00:24:00.540 --> 00:24:02.240

    Yeah, I think that's good.

    912

    00:24:02.680 --> 00:24:04.360

    So I know we've covered a lot

    913

    00:24:04.360 --> 00:24:06.380

    on guideline directed medical therapy,

    914

    00:24:06.420 --> 00:24:08.580

    but I think the urgency

    915

    00:24:08.580 --> 00:24:09.940

    to get a little bit

    916

    00:24:09.940 --> 00:24:12.660

    of those four pillars is so important

    917

    00:24:12.660 --> 00:24:14.140

    to reduce mortality,

    918

    00:24:14.360 --> 00:24:16.200

    not just reduce hospitalization.

    919

    00:24:16.240 --> 00:24:18.020

    And if you can help patients say

    920

    00:24:18.020 --> 00:24:19.240

    these medicines,

    921

    00:24:19.260 --> 00:24:21.340

    you may feel yucky when you first start.

    922

    00:24:21.400 --> 00:24:22.800

    And I always tell them that

    923

    00:24:22.800 --> 00:24:24.540

    because you're used to

    924

    00:24:24.540 --> 00:24:25.500

    high blood pressure

    925

    00:24:25.500 --> 00:24:28.220

    or you're used to being so short of breath.

    926

    00:24:28.520 --> 00:24:30.400

    But ultimately, these are going to help

    927

    00:24:30.400 --> 00:24:31.640

    keep you out of the hospital,

    928

    00:24:32.200 --> 00:24:34.180

    feel better and live longer.

    929

    00:24:34.700 --> 00:24:35.180

    Yeah.

    930

    00:24:35.780 --> 00:24:37.180

    Then you buy in.

    931

    00:24:37.520 --> 00:24:39.220

    Right. Yeah, yeah.

    932

    00:24:39.240 --> 00:24:41.160

    And and we do want to talk about

    933

    00:24:41.160 --> 00:24:43.420

    both echoes and anticoagulation.

    934

    00:24:43.520 --> 00:24:44.100

    If we have time,

    935

    00:24:44.140 --> 00:24:45.220

    I'd love to touch on half.

    936

    00:24:45.940 --> 00:24:47.960

    Our I always get half path

    937

    00:24:47.960 --> 00:24:49.460

    preserved as a fraction.

    938

    00:24:49.540 --> 00:24:50.000

    Yeah.

    939

    00:24:50.140 --> 00:24:52.220

    One thing I wanted to just mention

    940

    00:24:52.220 --> 00:24:53.180

    is diuretics.

    941

    00:24:53.460 --> 00:24:54.260

    I was just going to say that.

    942

    00:24:54.260 --> 00:24:55.360

    Can we touch on that first?

    943

    00:24:55.740 --> 00:24:57.420

    Yes, because this is so important.

    944

    00:24:57.540 --> 00:24:58.400

    What I get calls from,

    945

    00:24:58.460 --> 00:25:00.140

    how do you know this call

    946

    00:25:00.140 --> 00:25:01.080

    from the nursing home?

    947

    00:25:01.420 --> 00:25:04.460

    It was, uh, how much diuretic?

    948

    00:25:04.580 --> 00:25:05.160

    What should I do?

    949

    00:25:05.240 --> 00:25:06.780

    Here's an easy formula

    950

    00:25:06.780 --> 00:25:07.640

    for principle.

    951

    00:25:08.000 --> 00:25:09.860

    Pearl, double the diuretic

    952

    00:25:09.860 --> 00:25:10.940

    for two to three days.

    953

    00:25:11.240 --> 00:25:13.280

    If they're not responding to that

    954

    00:25:13.280 --> 00:25:15.760

    at Metola zone or xeroxyl in

    955

    00:25:15.760 --> 00:25:17.180

    two and a half milligrams

    956

    00:25:17.180 --> 00:25:19.920

    30 minutes before their morning dose.

    957

    00:25:19.920 --> 00:25:21.700

    So they're on multi dose.

    958

    00:25:22.640 --> 00:25:23.540

    If that doesn't work,

    959

    00:25:23.540 --> 00:25:25.400

    switch your loop diuretic

    960

    00:25:25.400 --> 00:25:26.660

    because loops, you know,

    961

    00:25:26.680 --> 00:25:28.800

    HCTZ I don't count as a diuretic

    962

    00:25:28.800 --> 00:25:29.340

    and heart failure.

    963

    00:25:29.480 --> 00:25:30.460

    It's really ineffective.

    964

    00:25:31.220 --> 00:25:32.760

    Any of those combo meds,

    965

    00:25:32.860 --> 00:25:33.420

    just, you know,

    966

    00:25:33.540 --> 00:25:34.900

    get them back on a pure medicine

    967

    00:25:34.900 --> 00:25:35.880

    and add a loop.

    968

    00:25:36.100 --> 00:25:36.500

    Exactly.

    969

    00:25:36.560 --> 00:25:37.900

    If they're on furosemide,

    970

    00:25:37.980 --> 00:25:39.060

    switch them to torsemide

    971

    00:25:39.060 --> 00:25:40.060

    because there's something called

    972

    00:25:40.060 --> 00:25:41.020

    diuretic tolerance.

    973

    00:25:41.320 --> 00:25:42.320

    I didn't know about that

    974

    00:25:42.320 --> 00:25:43.180

    for several years.

    975

    00:25:43.240 --> 00:25:43.720

    Yeah.

    976

    00:25:44.080 --> 00:25:45.720

    There's a dose response curve

    977

    00:25:45.720 --> 00:25:47.860

    to diuretics, but it's also

    978

    00:25:47.860 --> 00:25:49.580

    if you switch diuretics,

    979

    00:25:49.760 --> 00:25:50.320

    you may get,

    980

    00:25:51.340 --> 00:25:52.660

    even though it's the same class,

    981

    00:25:52.660 --> 00:25:53.760

    you may get a benefit.

    982

    00:25:54.220 --> 00:25:55.160

    Can you talk a bit about

    983

    00:25:55.160 --> 00:25:56.200

    the dose response curve

    984

    00:25:56.200 --> 00:25:57.600

    for the new people?

    985

    00:25:58.120 --> 00:25:58.320

    Sure.

    986

    00:25:58.660 --> 00:25:59.660

    So from, you know,

    987

    00:25:59.660 --> 00:26:01.520

    we think that each time

    988

    00:26:01.520 --> 00:26:02.640

    you like double a dose,

    989

    00:26:02.640 --> 00:26:04.240

    so you're going from 20 of LASIX

    990

    00:26:04.240 --> 00:26:05.300

    to 40 of LASIX,

    991

    00:26:05.300 --> 00:26:06.840

    you should get a better response,

    992

    00:26:07.000 --> 00:26:08.660

    but there's a ceiling effect.

    993

    00:26:08.700 --> 00:26:11.500

    So you get it up to a certain amount

    994

    00:26:11.500 --> 00:26:13.520

    and I would have to look at the chart

    995

    00:26:13.520 --> 00:26:15.940

    to be honest to see what that amount is.

    996

    00:26:16.640 --> 00:26:17.320

    But you're like,

    997

    00:26:17.320 --> 00:26:18.380

    well, just keep titrating

    998

    00:26:18.380 --> 00:26:19.620

    and keep titrating.

    999

    00:26:19.980 --> 00:26:22.640

    Now, the salient point about this

    1000

    00:26:22.640 --> 00:26:24.400

    is people go, I'm not peeing as much.

    1001

    00:26:24.420 --> 00:26:25.600

    Well, is that because

    1002

    00:26:25.600 --> 00:26:28.240

    their renal function is declining, right?

    1003

    00:26:28.660 --> 00:26:30.160

    Yeah, let's put that in there

    1004

    00:26:30.160 --> 00:26:31.120

    as a little curled up.

    1005

    00:26:31.120 --> 00:26:31.800

    Keep in your mind.

    1006

    00:26:31.920 --> 00:26:33.300

    Don't just focus on the diuretics.

    1007

    00:26:33.460 --> 00:26:34.300

    Think about the kidneys.

    1008

    00:26:34.580 --> 00:26:35.180

    Yes, go ahead.

    1009

    00:26:36.920 --> 00:26:38.980

    And also, you know,

    1010

    00:26:38.980 --> 00:26:40.560

    we tend not to fluid restrict people,

    1011

    00:26:40.560 --> 00:26:42.380

    but if they're not drinking a lot,

    1012

    00:26:42.500 --> 00:26:44.080

    is there anything to pee out?

    1013

    00:26:44.360 --> 00:26:46.460

    Like, you got to think that.

    1014

    00:26:46.980 --> 00:26:48.900

    So for folks with heart failure,

    1015

    00:26:49.240 --> 00:26:50.280

    you can titrate up.

    1016

    00:26:50.280 --> 00:26:52.100

    I mean, I've had patients on

    1017

    00:26:53.980 --> 00:26:55.760

    160 of Lasix twice a day.

    1018

    00:26:56.020 --> 00:26:57.460

    That's 320 in a day.

    1019

    00:26:57.800 --> 00:26:58.460

    That's a lot.

    1020

    00:26:58.660 --> 00:26:59.360

    That's a lot.

    1021

    00:27:00.840 --> 00:27:03.380

    But that's because I do this as a specialty.

    1022

    00:27:03.740 --> 00:27:05.480

    What I'm saying is you're also,

    1023

    00:27:05.600 --> 00:27:07.020

    if it's not effective anymore,

    1024

    00:27:07.040 --> 00:27:08.900

    it could be that they're not absorbing.

    1025

    00:27:09.380 --> 00:27:10.880

    So that's when you really need

    1026

    00:27:10.880 --> 00:27:12.000

    to consult cardiology.

    1027

    00:27:12.120 --> 00:27:14.620

    They just may need a dose of IV Lasix

    1028

    00:27:14.620 --> 00:27:15.740

    to get them over the hump.

    1029

    00:27:16.020 --> 00:27:16.780

    Oh, interesting.

    1030

    00:27:17.280 --> 00:27:18.020

    So I have a question.

    1031

    00:27:19.120 --> 00:27:20.700

    And one of the things I love about

    1032

    00:27:20.700 --> 00:27:22.300

    your teaching is how practical you are.

    1033

    00:27:22.300 --> 00:27:24.080

    So I'm just thinking practically for a moment.

    1034

    00:27:24.260 --> 00:27:25.820

    So if I have a patient in front of me,

    1035

    00:27:25.920 --> 00:27:27.000

    just applied, I mean,

    1036

    00:27:27.420 --> 00:27:29.280

    so if I have a patient in front of me

    1037

    00:27:29.280 --> 00:27:31.220

    and their weight is up,

    1038

    00:27:34.220 --> 00:27:35.760

    you can tell that they have edema

    1039

    00:27:35.760 --> 00:27:36.980

    in their lower extremities,

    1040

    00:27:37.040 --> 00:27:38.340

    but they're not short of breath.

    1041

    00:27:38.420 --> 00:27:39.400

    They're not having any chest pain,

    1042

    00:27:39.400 --> 00:27:40.020

    things like that.

    1043

    00:27:40.360 --> 00:27:41.320

    And it's like,

    1044

    00:27:41.320 --> 00:27:42.860

    oh, well, I did just have a holiday

    1045

    00:27:42.860 --> 00:27:44.640

    and I had a lot of salty food,

    1046

    00:27:44.740 --> 00:27:45.440

    things like that.

    1047

    00:27:46.280 --> 00:27:48.380

    The holiday season is tricky for that.

    1048

    00:27:50.060 --> 00:27:51.140

    That's the kind of situation

    1049

    00:27:51.140 --> 00:27:52.680

    if their blood pressure is stable,

    1050

    00:27:52.860 --> 00:27:53.400

    their heart rate is stable,

    1051

    00:27:53.500 --> 00:27:54.260

    all that stuff is stable.

    1052

    00:27:54.360 --> 00:27:55.580

    That's when I would probably

    1053

    00:27:55.580 --> 00:27:56.800

    want to double that dose

    1054

    00:27:56.800 --> 00:27:58.020

    for two to three days

    1055

    00:27:58.020 --> 00:27:59.800

    and then have them,

    1056

    00:27:59.840 --> 00:28:01.600

    what is that follow-up process look like,

    1057

    00:28:01.620 --> 00:28:02.460

    especially for new grads

    1058

    00:28:02.460 --> 00:28:05.340

    who are paranoid about lab function.

    1059

    00:28:06.200 --> 00:28:07.860

    How recent should their labs have been?

    1060

    00:28:07.920 --> 00:28:08.780

    How do I know if their kidneys

    1061

    00:28:08.780 --> 00:28:10.260

    can handle that for three days?

    1062

    00:28:10.340 --> 00:28:11.400

    Should I check their labs immediately?

    1063

    00:28:11.460 --> 00:28:12.660

    Am I going to put them in renal failure?

    1064

    00:28:13.520 --> 00:28:15.100

    Like, I'm just zooming back to my...

    1065

    00:28:15.100 --> 00:28:15.880

    The angst, I hear it.

    1066

    00:28:16.400 --> 00:28:18.220

    So you just described somebody

    1067

    00:28:18.220 --> 00:28:19.420

    who is warm and wet.

    1068

    00:28:19.580 --> 00:28:20.860

    There's this beautiful cascade

    1069

    00:28:20.860 --> 00:28:22.820

    that talks about warm and wet,

    1070

    00:28:22.960 --> 00:28:24.120

    cold and wet, right?

    1071

    00:28:24.420 --> 00:28:26.620

    But warm and wet, they're perfused.

    1072

    00:28:26.620 --> 00:28:27.060

    Yes.

    1073

    00:28:27.460 --> 00:28:28.220

    Even if they're short,

    1074

    00:28:28.260 --> 00:28:29.700

    they may be short of breath, that's okay,

    1075

    00:28:29.700 --> 00:28:32.300

    but they're hemodynamically stable, right?

    1076

    00:28:32.360 --> 00:28:34.380

    It's not a specific blood pressure number.

    1077

    00:28:34.740 --> 00:28:36.600

    My blood pressure runs in the 90s.

    1078

    00:28:36.760 --> 00:28:38.440

    If mine's in the 80s, that's a problem.

    1079

    00:28:38.580 --> 00:28:40.220

    But if I'm 90 to 100,

    1080

    00:28:40.500 --> 00:28:42.880

    you can still diurese me, morally.

    1081

    00:28:44.260 --> 00:28:46.120

    Oh my God, that's so scary for someone in New York.

    1082

    00:28:46.380 --> 00:28:47.540

    I know, I know.

    1083

    00:28:47.640 --> 00:28:49.860

    But remember, if they're walking around,

    1084

    00:28:49.860 --> 00:28:52.240

    walking, talking, well perfused,

    1085

    00:28:52.500 --> 00:28:54.360

    you feel a distal pulse, right?

    1086

    00:28:54.400 --> 00:28:57.160

    They're not cold and clammy, okay?

    1087

    00:28:57.660 --> 00:28:58.900

    People are walking around

    1088

    00:28:58.900 --> 00:29:02.040

    without their electrolytes checked every single day.

    1089

    00:29:02.380 --> 00:29:05.380

    All we do in primary care, outpatient care,

    1090

    00:29:05.680 --> 00:29:06.560

    is do a snapshot.

    1091

    00:29:06.920 --> 00:29:07.800

    There's a Polaroid picture

    1092

    00:29:07.800 --> 00:29:09.920

    or an iPhone picture of your labs.

    1093

    00:29:10.120 --> 00:29:10.840

    That's today.

    1094

    00:29:11.780 --> 00:29:14.620

    You could eat a whole bunch of, you know,

    1095

    00:29:14.780 --> 00:29:16.360

    I don't know, high potassium foods

    1096

    00:29:16.360 --> 00:29:17.520

    and your potassium go up,

    1097

    00:29:17.520 --> 00:29:19.240

    but your kidneys should adjust.

    1098

    00:29:19.240 --> 00:29:22.600

    So you should feel okay looking at,

    1099

    00:29:22.860 --> 00:29:24.800

    I did labs today, right?

    1100

    00:29:24.880 --> 00:29:26.540

    This is where I know I'm starting.

    1101

    00:29:26.740 --> 00:29:27.180

    Yeah.

    1102

    00:29:27.560 --> 00:29:29.700

    Or I saw them within the past month.

    1103

    00:29:29.720 --> 00:29:31.860

    I wouldn't go like six months worth of labs.

    1104

    00:29:31.940 --> 00:29:33.000

    I might go two months.

    1105

    00:29:33.000 --> 00:29:34.160

    So I saw you two months ago.

    1106

    00:29:34.280 --> 00:29:36.240

    You're now messaging, calling.

    1107

    00:29:36.760 --> 00:29:37.880

    You're fluid overloaded.

    1108

    00:29:37.940 --> 00:29:39.940

    I don't need you to come in for a visit today.

    1109

    00:29:40.220 --> 00:29:42.480

    I'm going to double your 40 LASIX.

    1110

    00:29:42.480 --> 00:29:44.420

    You're going to take it twice a day

    1111

    00:29:44.420 --> 00:29:46.100

    for the next two days and call me back.

    1112

    00:29:46.340 --> 00:29:47.760

    If you're not feeling better,

    1113

    00:29:47.760 --> 00:29:49.500

    I'm going to have you come in the office.

    1114

    00:29:49.500 --> 00:29:50.720

    I'm going to draw labs.

    1115

    00:29:51.040 --> 00:29:52.100

    If you are feeling better,

    1116

    00:29:52.280 --> 00:29:54.460

    I'm going to have you come for a lab only visit.

    1117

    00:29:54.780 --> 00:29:55.260

    Nice.

    1118

    00:29:55.600 --> 00:29:57.960

    I evaluate you over the phone.

    1119

    00:29:58.160 --> 00:29:59.640

    I did an intervention.

    1120

    00:29:59.820 --> 00:30:01.080

    I'm following up.

    1121

    00:30:01.160 --> 00:30:01.400

    Yeah.

    1122

    00:30:01.400 --> 00:30:03.800

    You don't need potassium levels every day.

    1123

    00:30:03.800 --> 00:30:04.180

    Yeah.

    1124

    00:30:04.180 --> 00:30:06.080

    You know, you could look at trends.

    1125

    00:30:06.360 --> 00:30:08.200

    If this is somebody who's followed, right?

    1126

    00:30:08.200 --> 00:30:11.360

    Oh, this person runs about three, three, five, three, six.

    1127

    00:30:11.660 --> 00:30:14.760

    Maybe I'll have them supplement with dietary

    1128

    00:30:14.760 --> 00:30:17.660

    or maybe I need to give them a potassium supplement.

    1129

    00:30:17.660 --> 00:30:19.860

    You know, for a couple of days.

    1130

    00:30:20.480 --> 00:30:20.540

    Yeah.

    1131

    00:30:20.540 --> 00:30:20.800

    Yeah.

    1132

    00:30:21.040 --> 00:30:24.220

    But that's a calming way to say,

    1133

    00:30:24.820 --> 00:30:27.080

    yeah, totally safe.

    1134

    00:30:27.460 --> 00:30:27.960

    Very safe.

    1135

    00:30:28.000 --> 00:30:29.600

    You're not going to drop someone's blood pressure.

    1136

    00:30:29.640 --> 00:30:33.780

    They're not going to pass out really two to three days.

    1137

    00:30:33.960 --> 00:30:35.180

    And how did they respond?

    1138

    00:30:35.440 --> 00:30:36.560

    Because you're right.

    1139

    00:30:36.700 --> 00:30:38.440

    Holiday eating, funeral eating.

    1140

    00:30:38.600 --> 00:30:41.820

    I do all sorts of counseling related to that,

    1141

    00:30:41.820 --> 00:30:43.660

    that trip people up.

    1142

    00:30:44.300 --> 00:30:44.460

    Absolutely.

    1143

    00:30:44.460 --> 00:30:46.880

    And I just, I do want to stress again that like

    1144

    00:30:47.980 --> 00:30:50.420

    if you're just, it doesn't matter how much experience you have,

    1145

    00:30:50.420 --> 00:30:52.520

    if you're uncomfortable, just asking for help.

    1146

    00:30:52.700 --> 00:30:55.220

    Because I mean, I'm asking you these questions being like,

    1147

    00:30:55.300 --> 00:30:56.280

    okay, I'm going to write this down.

    1148

    00:30:56.300 --> 00:30:57.240

    I'm going to bring this back, right?

    1149

    00:30:57.500 --> 00:31:00.300

    I'm writing all this stuff down and I, yeah,

    1150

    00:31:01.460 --> 00:31:03.020

    there's no shame in asking for help.

    1151

    00:31:03.200 --> 00:31:04.680

    And there's no expectation to know it.

    1152

    00:31:05.180 --> 00:31:05.940

    So yeah.

    1153

    00:31:06.100 --> 00:31:09.400

    And I'll just tell you like antibiotics are my nemesis.

    1154

    00:31:09.520 --> 00:31:14.100

    Every time I have a patient that I know they have a complicated UTI

    1155

    00:31:14.100 --> 00:31:16.460

    or I know that they have pneumonia.

    1156

    00:31:16.460 --> 00:31:18.040

    I don't send them for a chest x-ray.

    1157

    00:31:18.260 --> 00:31:20.860

    I actually listen for egopony, but I have to treat.

    1158

    00:31:20.980 --> 00:31:23.300

    And I'm like, oh darn, they're on all these other meds.

    1159

    00:31:23.420 --> 00:31:27.580

    So I have to go look up antibiotics for this treatment

    1160

    00:31:27.580 --> 00:31:30.260

    based on the creatinine, EGFR.

    1161

    00:31:30.560 --> 00:31:31.680

    Like I don't know that.

    1162

    00:31:32.200 --> 00:31:36.000

    So you can do anything for a long time, but you have to be safe.

    1163

    00:31:36.280 --> 00:31:36.740

    Totally.

    1164

    00:31:37.040 --> 00:31:37.080

    Right.

    1165

    00:31:37.400 --> 00:31:40.340

    Do you have any thoughts to add about people with,

    1166

    00:31:40.340 --> 00:31:43.780

    I think people also get really uncomfortable with decreased renal function

    1167

    00:31:43.780 --> 00:31:45.260

    with diuresis.

    1168

    00:31:45.260 --> 00:31:47.840

    Like if you have that kind of combination of heart failure,

    1169

    00:31:48.120 --> 00:31:50.000

    fluid overload and reduced kidney function,

    1170

    00:31:50.040 --> 00:31:51.900

    do you have any like kind of pearls there for people?

    1171

    00:31:52.220 --> 00:31:54.140

    Because I know nephrologists do a ton of like,

    1172

    00:31:54.140 --> 00:31:56.400

    there's always like that argument between like, you know,

    1173

    00:31:57.620 --> 00:32:00.180

    nephrologists and cardiologists of like what we should do or whatever.

    1174

    00:32:00.400 --> 00:32:02.060

    But yeah, do you have any pearls about that?

    1175

    00:32:03.360 --> 00:32:03.800

    Absolutely.

    1176

    00:32:04.140 --> 00:32:05.640

    Because this is something I really,

    1177

    00:32:05.880 --> 00:32:09.140

    I always paid attention to BUN and creatinine, BUN and creatinine.

    1178

    00:32:09.180 --> 00:32:13.400

    And yet with the newer meds, especially like the SGLT2s,

    1179

    00:32:14.560 --> 00:32:16.760

    glomerulofiltration rate, EGFR.

    1180

    00:32:16.920 --> 00:32:20.860

    So I am so biased because most of my patients don't have a normal creatinine.

    1181

    00:32:22.280 --> 00:32:24.840

    But here's the thing, creatinine is that snapshot.

    1182

    00:32:24.880 --> 00:32:26.500

    Again, it fluctuates up and down.

    1183

    00:32:26.720 --> 00:32:29.240

    Your GFR is what you're really impacting.

    1184

    00:32:29.840 --> 00:32:34.040

    And remember that people who are in heart failure with congestion

    1185

    00:32:34.040 --> 00:32:37.340

    often have an elevated creatinine.

    1186

    00:32:37.340 --> 00:32:40.940

    And then you take the fluid off and guess what happens to the creatinine?

    1187

    00:32:41.020 --> 00:32:42.100

    It goes down.

    1188

    00:32:42.380 --> 00:32:42.800

    Cool.

    1189

    00:32:42.800 --> 00:32:47.300

    So like, oh, oh my gosh, I'm seeing a creatinine of 1.9.

    1190

    00:32:47.300 --> 00:32:48.080

    I'm freaking out.

    1191

    00:32:48.080 --> 00:32:49.420

    I don't want to diurese them.

    1192

    00:32:49.420 --> 00:32:50.540

    I'm going to damage their kidneys.

    1193

    00:32:51.000 --> 00:32:54.020

    No, no, no, because they're symptomatic.

    1194

    00:32:54.120 --> 00:32:57.500

    So you look at their GFR, their GFR may be dipped down a little,

    1195

    00:32:57.500 --> 00:32:59.760

    but it's not going to go below 30, right?

    1196

    00:32:59.760 --> 00:33:01.540

    With the creatinine of 1.9.

    1197

    00:33:01.640 --> 00:33:02.800

    I'm going to diurese them.

    1198

    00:33:02.940 --> 00:33:03.520

    And guess what?

    1199

    00:33:03.840 --> 00:33:05.280

    The creatinine comes back 1.2.

    1200

    00:33:05.320 --> 00:33:08.380

    And you're like, oh, they feel better.

    1201

    00:33:08.820 --> 00:33:10.300

    But that freaked me out.

    1202

    00:33:10.440 --> 00:33:11.180

    I couldn't understand.

    1203

    00:33:11.180 --> 00:33:12.820

    I was like, wait, wait.

    1204

    00:33:13.240 --> 00:33:18.660

    So the rule about creatinine is really a 0.3 change.

    1205

    00:33:20.940 --> 00:33:24.820

    Your therapy shouldn't change the creatinine more than 0.3.

    1206

    00:33:25.020 --> 00:33:26.600

    That's when you start getting concerned.

    1207

    00:33:26.840 --> 00:33:27.880

    Cool, cool.

    1208

    00:33:28.320 --> 00:33:29.880

    I love those concrete pearls.

    1209

    00:33:29.980 --> 00:33:30.520

    They're so helpful.

    1210

    00:33:31.100 --> 00:33:33.440

    That is like one of my, oh, what did I do?

    1211

    00:33:33.520 --> 00:33:34.340

    And look at trends.

    1212

    00:33:34.660 --> 00:33:37.500

    Like just in your other episode, you mentioned like BNP.

    1213

    00:33:37.820 --> 00:33:39.580

    We don't treat BNP.

    1214

    00:33:39.640 --> 00:33:40.640

    We treat trends.

    1215

    00:33:40.640 --> 00:33:44.680

    We look at creatinine trends.

    1216

    00:33:44.920 --> 00:33:46.740

    What's baseline for that person?

    1217

    00:33:47.860 --> 00:33:49.920

    And remember, they're going to look at their labs and go,

    1218

    00:33:50.100 --> 00:33:51.800

    it says I'm in moderate kidney failure.

    1219

    00:33:52.180 --> 00:33:55.540

    Yes, because you've had heart failure for a while.

    1220

    00:33:56.660 --> 00:33:58.940

    And we're continuously monitoring it.

    1221

    00:33:58.960 --> 00:34:00.000

    And we're supporting it.

    1222

    00:34:00.000 --> 00:34:00.940

    Do I need dialysis?

    1223

    00:34:01.280 --> 00:34:03.000

    You don't need dialysis.

    1224

    00:34:03.320 --> 00:34:05.640

    But they read those interpretations.

    1225

    00:34:05.760 --> 00:34:08.280

    And you're now getting panic calls.

    1226

    00:34:08.280 --> 00:34:11.380

    So just relax.

    1227

    00:34:11.420 --> 00:34:13.800

    But I think that's probably one of those other things

    1228

    00:34:13.800 --> 00:34:14.659

    that took me a while.

    1229

    00:34:14.980 --> 00:34:16.520

    What's your filtration rate?

    1230

    00:34:16.580 --> 00:34:18.440

    Let's look at how your kidneys are really

    1231

    00:34:18.440 --> 00:34:20.480

    filtering the toxins in your body.

    1232

    00:34:20.560 --> 00:34:22.800

    And then it helps us both understand.

    1233

    00:34:23.820 --> 00:34:24.659

    Definitely, definitely.

    1234

    00:34:25.179 --> 00:34:26.500

    So here's the thing about echoes.

    1235

    00:34:26.719 --> 00:34:29.340

    I think your previous Cardiology NP speaker

    1236

    00:34:29.340 --> 00:34:31.460

    did a great job of talking about like

    1237

    00:34:31.460 --> 00:34:33.100

    which diagnostic test to order.

    1238

    00:34:33.380 --> 00:34:36.139

    But just in case folks haven't seen that episode,

    1239

    00:34:36.400 --> 00:34:37.980

    I think a couple of things to remember.

    1240

    00:34:38.280 --> 00:34:41.020

    First is, why am I getting this test, right?

    1241

    00:34:41.159 --> 00:34:43.920

    I always go, you have to know why you're getting it.

    1242

    00:34:43.960 --> 00:34:45.719

    So for simple things like,

    1243

    00:34:46.060 --> 00:34:47.699

    I look at the structure of the heart,

    1244

    00:34:47.880 --> 00:34:50.120

    the valves and the ejection fraction,

    1245

    00:34:50.239 --> 00:34:52.560

    the function of the left ventricle, right?

    1246

    00:34:52.900 --> 00:34:53.699

    That's simple.

    1247

    00:34:54.480 --> 00:34:57.620

    Do I have a patient with known valve disease

    1248

    00:34:57.620 --> 00:35:01.180

    that I want to look at progression over time, right?

    1249

    00:35:02.140 --> 00:35:04.080

    As far as ejection fraction goes,

    1250

    00:35:04.080 --> 00:35:07.760

    you also want to have patience on adequate therapy

    1251

    00:35:07.760 --> 00:35:09.140

    for at least three months.

    1252

    00:35:09.480 --> 00:35:10.980

    So patients sometimes get a little eager.

    1253

    00:35:11.140 --> 00:35:12.140

    You started me on the medicine.

    1254

    00:35:12.320 --> 00:35:13.400

    Is my ejection fraction better?

    1255

    00:35:13.480 --> 00:35:14.280

    Is it better? Is it better?

    1256

    00:35:14.300 --> 00:35:17.080

    And you're like, whoa, it takes a couple months.

    1257

    00:35:17.620 --> 00:35:19.380

    Three months is the magic number.

    1258

    00:35:19.740 --> 00:35:22.180

    Don't do anything until they've been

    1259

    00:35:22.180 --> 00:35:23.920

    on good therapies for three months.

    1260

    00:35:24.500 --> 00:35:29.960

    The other thing is looking at the left ventricle.

    1261

    00:35:29.980 --> 00:35:33.500

    And you see words like achinetic, hypocontractile,

    1262

    00:35:33.740 --> 00:35:34.780

    and a dyskinetic.

    1263

    00:35:34.980 --> 00:35:37.120

    I'm like, what do all these things mean, right?

    1264

    00:35:37.120 --> 00:35:39.500

    Well, achinetic is pretty easy.

    1265

    00:35:40.120 --> 00:35:42.520

    A absence of kinetic movement.

    1266

    00:35:42.900 --> 00:35:43.660

    So no movement.

    1267

    00:35:44.160 --> 00:35:46.400

    So if I see an echo report

    1268

    00:35:46.400 --> 00:35:49.040

    that says the inferior wall is achinetic,

    1269

    00:35:49.340 --> 00:35:50.340

    do you know what I know?

    1270

    00:35:50.680 --> 00:35:52.980

    A person probably had an inferior MI

    1271

    00:35:52.980 --> 00:35:54.220

    because it's dead.

    1272

    00:35:54.640 --> 00:35:55.780

    It's not moving.

    1273

    00:35:56.320 --> 00:35:57.520

    We're not going to fix that.

    1274

    00:35:57.760 --> 00:35:58.540

    It's gone.

    1275

    00:35:59.200 --> 00:36:02.060

    Versus hypokinetic or hypocontractile,

    1276

    00:36:02.080 --> 00:36:03.300

    depending on how your echo.

    1277

    00:36:03.700 --> 00:36:06.020

    That means there's options to improve that area,

    1278

    00:36:06.020 --> 00:36:07.560

    especially if it's in a region.

    1279

    00:36:08.120 --> 00:36:11.760

    So maybe this is a person who has no coronary disease

    1280

    00:36:11.760 --> 00:36:14.300

    and might need angioplasty,

    1281

    00:36:14.440 --> 00:36:16.100

    might need bypass surgery.

    1282

    00:36:16.360 --> 00:36:17.920

    It's not for you to decide,

    1283

    00:36:18.160 --> 00:36:20.080

    but looking at an echo report,

    1284

    00:36:20.100 --> 00:36:22.000

    I always say, what's the quality of it?

    1285

    00:36:22.380 --> 00:36:24.320

    They say poor, moderate,

    1286

    00:36:24.520 --> 00:36:25.680

    nobody ever says excellent.

    1287

    00:36:25.900 --> 00:36:27.400

    And then you go down

    1288

    00:36:27.400 --> 00:36:29.420

    and you look at left ventricle wall motion.

    1289

    00:36:29.620 --> 00:36:30.880

    There's about six different,

    1290

    00:36:31.620 --> 00:36:33.760

    does it say global hypocontractility?

    1291

    00:36:33.760 --> 00:36:38.120

    More than likely it's an etiology that's not ischemic,

    1292

    00:36:38.380 --> 00:36:39.360

    not reversible.

    1293

    00:36:39.820 --> 00:36:41.100

    So from a virus,

    1294

    00:36:41.700 --> 00:36:43.080

    from chemotherapy,

    1295

    00:36:43.840 --> 00:36:45.340

    from peripartum.

    1296

    00:36:46.000 --> 00:36:49.120

    So global hypocontractility or hypokinesis,

    1297

    00:36:50.360 --> 00:36:52.060

    you hope to improve the function,

    1298

    00:36:52.360 --> 00:36:55.160

    but that's less likely an ischemic origin.

    1299

    00:36:55.700 --> 00:36:57.200

    Then you look at the ejection fraction.

    1300

    00:36:58.080 --> 00:36:59.880

    Is it less than or equal to 40?

    1301

    00:37:00.120 --> 00:37:01.940

    Is it that 41 to 49?

    1302

    00:37:02.260 --> 00:37:03.560

    Or is it 50 and over?

    1303

    00:37:03.560 --> 00:37:06.560

    And that kind of gives you your three buckets of treatment.

    1304

    00:37:07.860 --> 00:37:09.000

    And then the last thing I look at,

    1305

    00:37:09.020 --> 00:37:10.200

    what is their interpretation?

    1306

    00:37:10.540 --> 00:37:11.680

    Is this their second echo,

    1307

    00:37:11.820 --> 00:37:12.840

    their 14th echo?

    1308

    00:37:12.980 --> 00:37:14.620

    Is it worse, better, or the same?

    1309

    00:37:15.740 --> 00:37:17.640

    Now, there's a special group that I think,

    1310

    00:37:18.040 --> 00:37:20.640

    you see tons of patients in AFib, right?

    1311

    00:37:21.700 --> 00:37:24.320

    And it could be paroxysmal, chronic, bless you.

    1312

    00:37:24.460 --> 00:37:25.960

    It's more pervasive than ever.

    1313

    00:37:26.460 --> 00:37:27.720

    One of the things that I learned

    1314

    00:37:27.720 --> 00:37:29.560

    from an electrophysiologist is

    1315

    00:37:29.560 --> 00:37:31.060

    if you're getting an echo

    1316

    00:37:31.060 --> 00:37:33.420

    and you think, oh, well, my patient's in AFib,

    1317

    00:37:33.420 --> 00:37:35.440

    they're going to go for a cardioversion.

    1318

    00:37:35.740 --> 00:37:38.400

    If their left atrium is dilated,

    1319

    00:37:38.640 --> 00:37:39.940

    and I'm not going to give you numbers

    1320

    00:37:39.940 --> 00:37:40.840

    because it doesn't matter.

    1321

    00:37:40.860 --> 00:37:43.280

    Just look if it says severely enlarged,

    1322

    00:37:43.300 --> 00:37:44.480

    nail or woman,

    1323

    00:37:44.760 --> 00:37:46.220

    you are not going to cardiovert.

    1324

    00:37:46.300 --> 00:37:47.600

    And here's how I describe it.

    1325

    00:37:47.740 --> 00:37:49.520

    That atrium is so dilated,

    1326

    00:37:49.620 --> 00:37:51.360

    the electrical system's distorted.

    1327

    00:37:51.880 --> 00:37:54.960

    There's no way a shock is going to make it better.

    1328

    00:37:56.440 --> 00:37:59.280

    So that's when they might need an ablation.

    1329

    00:37:59.360 --> 00:38:00.900

    They might need meds titrated.

    1330

    00:38:00.900 --> 00:38:03.240

    But that's another kind of pearl of,

    1331

    00:38:04.200 --> 00:38:06.860

    oh, this patient's stable in their AFib,

    1332

    00:38:06.900 --> 00:38:09.040

    but I'm going to look what their atrial size is

    1333

    00:38:09.040 --> 00:38:13.440

    in case they're thinking about cardioversion, right?

    1334

    00:38:14.480 --> 00:38:16.820

    So that was one of those, huh?

    1335

    00:38:16.940 --> 00:38:18.040

    It's just not effective.

    1336

    00:38:18.280 --> 00:38:19.620

    Yeah. Oh, I love that.

    1337

    00:38:20.260 --> 00:38:20.520

    Cool.

    1338

    00:38:20.660 --> 00:38:23.560

    So that's really like the main things of an echo

    1339

    00:38:23.560 --> 00:38:26.200

    is don't get mired in the details.

    1340

    00:38:26.540 --> 00:38:28.420

    Again, you're comparing a prior echo.

    1341

    00:38:28.580 --> 00:38:30.760

    You're looking for improvement on therapy.

    1342

    00:38:30.900 --> 00:38:34.320

    Because maybe they'll need a defibrillator or a pacemaker.

    1343

    00:38:35.120 --> 00:38:37.500

    The last thing I know you wanted to talk about

    1344

    00:38:37.500 --> 00:38:38.840

    was anticoagulation.

    1345

    00:38:39.380 --> 00:38:40.580

    Yeah, absolutely.

    1346

    00:38:40.800 --> 00:38:43.340

    I mean, there's so many questions.

    1347

    00:38:44.460 --> 00:38:46.640

    Yeah, so, well, the context for this question was

    1348

    00:38:48.760 --> 00:38:50.120

    people, I think that, I guess,

    1349

    00:38:50.760 --> 00:38:52.280

    I also like to give examples

    1350

    00:38:52.280 --> 00:38:54.920

    because it really normalizes the imposter syndrome

    1351

    00:38:54.920 --> 00:38:56.520

    for new grads of like, you're not alone.

    1352

    00:38:56.840 --> 00:38:58.280

    We all feel this way or felt this way.

    1353

    00:38:58.940 --> 00:39:01.220

    But yeah, I think there's a lot of discomfort around.

    1354

    00:39:01.460 --> 00:39:03.220

    So I've had a lot of students, for example,

    1355

    00:39:04.200 --> 00:39:06.620

    that they will hear in a regular heartbeat,

    1356

    00:39:06.700 --> 00:39:11.540

    they will do an EKG and they'll be like hands shaking,

    1357

    00:39:11.560 --> 00:39:13.040

    like, is this, what is this?

    1358

    00:39:13.100 --> 00:39:14.360

    And I'm like, well, what do you think it is?

    1359

    00:39:14.380 --> 00:39:15.300

    And I'm like, I think it's AFib.

    1360

    00:39:15.380 --> 00:39:16.420

    I'm like, well, it is AFib.

    1361

    00:39:16.500 --> 00:39:18.140

    And they're like, okay, so I just like refer it.

    1362

    00:39:18.140 --> 00:39:18.740

    Like, what should I do?

    1363

    00:39:18.760 --> 00:39:20.520

    And it's like, oh, no, no, like, what else should I do?

    1364

    00:39:20.540 --> 00:39:22.480

    I'm like, no, no, that's like your diagnosis.

    1365

    00:39:22.600 --> 00:39:23.760

    Like you made a diagnosis.

    1366

    00:39:24.280 --> 00:39:26.680

    Like, congratulations, AFib, you made a diagnosis.

    1367

    00:39:26.780 --> 00:39:26.980

    Great.

    1368

    00:39:26.980 --> 00:39:28.760

    So what are you going to do about that?

    1369

    00:39:29.180 --> 00:39:32.740

    And so, and I think that there's like a panic moment there

    1370

    00:39:32.740 --> 00:39:34.100

    of like a new diagnosis.

    1371

    00:39:34.240 --> 00:39:37.300

    And then there's also the people who are on things already.

    1372

    00:39:38.060 --> 00:39:40.960

    And I know like, I guess the variables to think about are,

    1373

    00:39:42.080 --> 00:39:43.540

    and I've touched on this a little bit,

    1374

    00:39:43.640 --> 00:39:45.500

    but I feel like professors and different perspectives

    1375

    00:39:45.500 --> 00:39:46.300

    are always so helpful.

    1376

    00:39:46.460 --> 00:39:47.940

    But like, what are your kind of steps

    1377

    00:39:47.940 --> 00:39:49.840

    when it comes to either a new diagnosis

    1378

    00:39:49.840 --> 00:39:53.740

    or somebody who is already on medications?

    1379

    00:39:53.800 --> 00:39:56.460

    And like, we're thinking about the treatment options of like,

    1380

    00:39:56.460 --> 00:39:58.420

    we can kind of just keep it to the two main categories,

    1381

    00:39:58.420 --> 00:39:59.520

    unless you want to add more things,

    1382

    00:39:59.540 --> 00:40:02.600

    but the DOACs and then Warfarin basically

    1383

    00:40:02.600 --> 00:40:05.160

    are the two kind of main categories, at least that I see.

    1384

    00:40:06.000 --> 00:40:07.700

    Yeah, so what are your thoughts about that?

    1385

    00:40:07.880 --> 00:40:11.680

    Okay, so I have some easy confidence building tools

    1386

    00:40:11.680 --> 00:40:13.320

    for folks, right?

    1387

    00:40:13.660 --> 00:40:16.380

    Because this was my panic area.

    1388

    00:40:17.240 --> 00:40:17.500

    Oh, totally.

    1389

    00:40:17.620 --> 00:40:18.840

    No, and I'm giving an example

    1390

    00:40:18.840 --> 00:40:20.720

    because I also did that as a new grad, yes.

    1391

    00:40:21.320 --> 00:40:25.000

    Yes, so DOACs weren't invented when I started as an NP.

    1392

    00:40:25.140 --> 00:40:26.180

    So that is one thing.

    1393

    00:40:26.180 --> 00:40:30.100

    My first week of everybody left, I was on call

    1394

    00:40:30.100 --> 00:40:32.060

    and I was needing to manage Warfarin

    1395

    00:40:32.060 --> 00:40:35.520

    in about a million people, and I panicked.

    1396

    00:40:35.780 --> 00:40:38.420

    And luckily, I had a pharmacist who was a pharmacy fellow,

    1397

    00:40:38.440 --> 00:40:40.520

    so I had a local resource.

    1398

    00:40:40.960 --> 00:40:42.760

    And I ran everything by the attending

    1399

    00:40:42.760 --> 00:40:44.540

    to the point that he finally said,

    1400

    00:40:44.560 --> 00:40:45.840

    Mitch, would you stop calling me?

    1401

    00:40:45.860 --> 00:40:47.420

    You're giving me all the right answers.

    1402

    00:40:47.440 --> 00:40:48.640

    And I went, okay.

    1403

    00:40:49.760 --> 00:40:52.600

    So I now use this as a teaching tool in my class.

    1404

    00:40:52.600 --> 00:40:53.580

    We do an on-call sim.

    1405

    00:40:54.180 --> 00:40:57.820

    Say, so I'm going to start with Warfarin first, okay?

    1406

    00:40:58.180 --> 00:41:02.260

    And Warfarin, it's not just about this one dose.

    1407

    00:41:02.420 --> 00:41:03.780

    Again, if you look at lab results,

    1408

    00:41:03.800 --> 00:41:05.840

    there are always a snapshot in time.

    1409

    00:41:06.100 --> 00:41:07.180

    What you need to look at

    1410

    00:41:07.180 --> 00:41:10.200

    is the patient's total weekly dose, right?

    1411

    00:41:10.360 --> 00:41:11.600

    If you're making adjustments.

    1412

    00:41:11.960 --> 00:41:13.640

    And people say, but I have a nomogram

    1413

    00:41:13.640 --> 00:41:15.820

    or I have a chart or the pharmacist does this.

    1414

    00:41:15.820 --> 00:41:18.040

    And I'm like, you could be in the grocery store

    1415

    00:41:18.040 --> 00:41:19.640

    picking up children from ballet,

    1416

    00:41:19.860 --> 00:41:21.160

    getting the dog from the groomer.

    1417

    00:41:21.320 --> 00:41:22.900

    You have to know how to do this.

    1418

    00:41:24.200 --> 00:41:26.780

    So let's just pick a fib as an example.

    1419

    00:41:26.940 --> 00:41:29.120

    Your INR range is two to three.

    1420

    00:41:29.820 --> 00:41:32.700

    And say the person only wants to be on Warfarin.

    1421

    00:41:32.780 --> 00:41:33.740

    They trust Warfarin.

    1422

    00:41:33.800 --> 00:41:35.720

    They don't want to be on these other meds.

    1423

    00:41:36.000 --> 00:41:37.800

    So you get an INR.

    1424

    00:41:38.020 --> 00:41:40.540

    That's 1.5, right?

    1425

    00:41:41.140 --> 00:41:43.860

    You're going to look at what's the reason, right?

    1426

    00:41:43.860 --> 00:41:45.020

    If they've been taking their med,

    1427

    00:41:45.160 --> 00:41:46.460

    haven't missed any doses.

    1428

    00:41:47.360 --> 00:41:48.340

    You go through the Ds,

    1429

    00:41:48.420 --> 00:41:49.820

    has there been a change in diet?

    1430

    00:41:49.980 --> 00:41:51.180

    Are there any new drugs?

    1431

    00:41:51.180 --> 00:41:53.260

    And have they been drinking alcohol?

    1432

    00:41:53.620 --> 00:41:57.100

    Those are kind of my quick little nice diet,

    1433

    00:41:57.420 --> 00:42:02.240

    drugs, drinking, and drugs also refer to substances, right?

    1434

    00:42:02.920 --> 00:42:04.620

    And no missed doses.

    1435

    00:42:04.960 --> 00:42:09.240

    So now I say, wow, you are on five milligrams every day.

    1436

    00:42:09.560 --> 00:42:11.660

    Five times seven is 35.

    1437

    00:42:11.760 --> 00:42:14.600

    That's 35 milligrams total weekly dose.

    1438

    00:42:16.060 --> 00:42:16.600

    What did I say?

    1439

    00:42:16.600 --> 00:42:20.240

    They're on 1.6 and I need to get them to two, right?

    1440

    00:42:20.890 --> 00:42:25.520

    I want to increase that total weekly dose by 10 to 15%.

    1441

    00:42:27.740 --> 00:42:30.080

    You can go up to 20 if it was really low,

    1442

    00:42:30.100 --> 00:42:33.900

    but that's a safe way to do it, right?

    1443

    00:42:33.980 --> 00:42:35.820

    Today they're 1.6.

    1444

    00:42:37.620 --> 00:42:40.560

    10% of their total weekly dose is 3.5.

    1445

    00:42:41.220 --> 00:42:43.300

    I have to keep the math simple.

    1446

    00:42:45.220 --> 00:42:48.980

    Even if we said, okay, 15, maybe I'm going up four milligrams.

    1447

    00:42:48.980 --> 00:42:50.920

    Well, I look at what size tablets

    1448

    00:42:50.920 --> 00:42:52.940

    do they have at home too, right?

    1449

    00:42:53.300 --> 00:42:55.800

    I don't want such a rookie mistake that I would make yet.

    1450

    00:42:56.660 --> 00:42:59.120

    Tell me the strength of your tablet.

    1451

    00:42:59.680 --> 00:43:03.600

    If I say, I want to increase you to get you back

    1452

    00:43:03.600 --> 00:43:04.760

    to your therapeutic range.

    1453

    00:43:05.060 --> 00:43:06.420

    I'm going to have you take,

    1454

    00:43:08.640 --> 00:43:10.100

    break your five milligram tablet

    1455

    00:43:10.100 --> 00:43:12.800

    and take an extra two and a half tonight, Monday,

    1456

    00:43:13.380 --> 00:43:16.160

    and take another two and a half tomorrow night, right?

    1457

    00:43:16.160 --> 00:43:17.780

    That's five milligrams, Midge.

    1458

    00:43:17.920 --> 00:43:18.960

    You went up like 20%.

    1459

    00:43:19.680 --> 00:43:21.260

    Then have them check on Friday.

    1460

    00:43:22.720 --> 00:43:25.320

    There's lots of ways, but the easiest,

    1461

    00:43:25.560 --> 00:43:29.840

    remember it's their total weekly dose 10 to 15% up,

    1462

    00:43:30.080 --> 00:43:36.220

    10 to 15% down, and then check an INR several days later.

    1463

    00:43:36.560 --> 00:43:40.500

    Like I say within, because Warfarin has a longer half

    1464

    00:43:40.500 --> 00:43:42.000

    life than the DOACs, right?

    1465

    00:43:42.000 --> 00:43:43.320

    So you don't want to check it tomorrow

    1466

    00:43:43.320 --> 00:43:44.760

    like you do in the hospital.

    1467

    00:43:45.400 --> 00:43:50.380

    Three to four days later, safe formulaic plan,

    1468

    00:43:51.360 --> 00:43:57.820

    diet, drugs, drinking, misdoses, 10 to 15% up or down.

    1469

    00:43:58.280 --> 00:43:58.700

    That's so great.

    1470

    00:43:58.760 --> 00:44:01.740

    Just no mechanical valves are 2.5 to 3.5.

    1471

    00:44:01.780 --> 00:44:03.640

    So you've got to know your ranges, right?

    1472

    00:44:04.740 --> 00:44:06.200

    Yes, the reason for their anticoagulation.

    1473

    00:44:06.360 --> 00:44:07.960

    Yeah, exactly, exactly.

    1474

    00:44:08.020 --> 00:44:09.440

    But that's like the simple way.

    1475

    00:44:09.460 --> 00:44:10.660

    And then as far as the DOACs,

    1476

    00:44:10.700 --> 00:44:13.220

    my biggest message on these DOACs are

    1477

    00:44:14.020 --> 00:44:16.920

    we are so under treating our older adults.

    1478

    00:44:17.140 --> 00:44:21.420

    We are so worried about falls and a head bleed.

    1479

    00:44:21.740 --> 00:44:22.140

    Guess what?

    1480

    00:44:22.560 --> 00:44:27.040

    I think it's worse to have a head bleed

    1481

    00:44:27.040 --> 00:44:29.980

    and not be able to, you've just,

    1482

    00:44:30.700 --> 00:44:33.120

    it's worse to have a stroke, excuse me, than a head bleed.

    1483

    00:44:33.360 --> 00:44:34.880

    So here's some safe tools.

    1484

    00:44:35.300 --> 00:44:37.300

    You use the Chad's Vast Score,

    1485

    00:44:37.620 --> 00:44:39.160

    little calculator on everything.

    1486

    00:44:39.600 --> 00:44:42.640

    Have you ever heard of the HazBled, H-A-S, right?

    1487

    00:44:42.640 --> 00:44:44.320

    Yeah, but people might not have, so go.

    1488

    00:44:44.740 --> 00:44:47.380

    Right, so HazBled Score looks at your risk for bleeding.

    1489

    00:44:47.860 --> 00:44:49.800

    So if I'm saying, oh my goodness,

    1490

    00:44:49.840 --> 00:44:50.900

    I don't know what to do.

    1491

    00:44:51.400 --> 00:44:53.900

    Chad's Vast gives you formulas for,

    1492

    00:44:54.160 --> 00:44:54.980

    do they have heart failure?

    1493

    00:44:55.020 --> 00:44:55.860

    How old are they?

    1494

    00:44:55.900 --> 00:44:57.140

    Are they a man or a woman?

    1495

    00:44:57.200 --> 00:44:58.920

    Do they have vascular disease, right?

    1496

    00:44:59.060 --> 00:44:59.940

    Have they had a stroke?

    1497

    00:45:00.260 --> 00:45:01.220

    What's your stroke risk?

    1498

    00:45:01.940 --> 00:45:04.960

    HazBled looks at hypertension, liver function,

    1499

    00:45:05.180 --> 00:45:08.460

    bleeding history, history of labile INRs,

    1500

    00:45:08.500 --> 00:45:11.200

    my bleeding risk, and then you balance them out.

    1501

    00:45:11.920 --> 00:45:14.300

    And that's how you make a good,

    1502

    00:45:14.300 --> 00:45:16.080

    evidence-based clinical decision.

    1503

    00:45:16.400 --> 00:45:16.940

    And guess what?

    1504

    00:45:17.180 --> 00:45:18.440

    I put it in my notes.

    1505

    00:45:18.520 --> 00:45:20.140

    Yeah, totally.

    1506

    00:45:20.540 --> 00:45:22.620

    If I say Chad's Vast equals this,

    1507

    00:45:22.860 --> 00:45:23.820

    HazBled equals this,

    1508

    00:45:25.080 --> 00:45:25.560

    anticoagulate.

    1509

    00:45:26.060 --> 00:45:28.360

    I just learned, and I'm looking at this,

    1510

    00:45:28.500 --> 00:45:30.420

    it's called the SPARC tool, S-P-A-R-C.

    1511

    00:45:30.420 --> 00:45:32.040

    Oh yeah, yeah, yeah, you told me about that.

    1512

    00:45:32.220 --> 00:45:33.220

    I haven't looked at it yet.

    1513

    00:45:33.600 --> 00:45:34.180

    Yeah, go ahead.

    1514

    00:45:34.540 --> 00:45:37.900

    All it does is combine the Chad's Vast and the HazBled.

    1515

    00:45:38.160 --> 00:45:40.540

    I'm like, if they added in,

    1516

    00:45:40.540 --> 00:45:42.800

    are they on NSAIDs or antiplatelets?

    1517

    00:45:42.940 --> 00:45:44.920

    So that's important.

    1518

    00:45:45.560 --> 00:45:48.960

    But again, if we use evidence-based tools

    1519

    00:45:48.960 --> 00:45:54.040

    that are usually available either online or in an app,

    1520

    00:45:54.940 --> 00:45:56.820

    and document that in our note,

    1521

    00:45:57.640 --> 00:46:01.980

    then if the 92-year-old tripped and fell

    1522

    00:46:01.980 --> 00:46:05.880

    and hit their head, that's not on you.

    1523

    00:46:05.980 --> 00:46:07.300

    You've given good evidence

    1524

    00:46:07.300 --> 00:46:10.340

    because their risk of stroke was 58%.

    1525

    00:46:11.440 --> 00:46:13.220

    Yeah, and you've had the conversation

    1526

    00:46:13.220 --> 00:46:14.580

    with the patient as well.

    1527

    00:46:14.700 --> 00:46:15.920

    And you've had shared decision-making.

    1528

    00:46:16.040 --> 00:46:17.580

    Right, it's all about that,

    1529

    00:46:17.580 --> 00:46:19.220

    of what do you want to do?

    1530

    00:46:19.640 --> 00:46:21.600

    So that's pretty much my passion.

    1531

    00:46:21.920 --> 00:46:23.320

    There are reversal agents.

    1532

    00:46:23.380 --> 00:46:25.200

    I haven't had to use any of them for these.

    1533

    00:46:25.360 --> 00:46:29.100

    Several of like a Pixaban and Dabigatran and a Doxaban.

    1534

    00:46:30.000 --> 00:46:31.680

    There are reversal agents for them now,

    1535

    00:46:31.680 --> 00:46:33.180

    which is also a benefit.

    1536

    00:46:33.520 --> 00:46:35.060

    So if you're concerned,

    1537

    00:46:35.820 --> 00:46:38.640

    you and I aren't measuring Factor Xa levels

    1538

    00:46:38.640 --> 00:46:40.180

    as a routine practice.

    1539

    00:46:41.060 --> 00:46:43.180

    I don't want the folks who may work

    1540

    00:46:43.180 --> 00:46:44.880

    at an academic health center

    1541

    00:46:44.880 --> 00:46:46.720

    and then their brand new NP is going,

    1542

    00:46:47.000 --> 00:46:49.520

    I'd like a Factor Xa level and I'd like this and this.

    1543

    00:46:49.920 --> 00:46:50.400

    Like, whoa, whoa, whoa.

    1544

    00:46:50.440 --> 00:46:51.800

    No, no, no.

    1545

    00:46:51.800 --> 00:46:53.460

    No, no, no, no, no.

    1546

    00:46:53.460 --> 00:46:57.060

    Cost stewardship and really what does the patient need?

    1547

    00:46:57.100 --> 00:46:59.300

    And I think for your listeners, Liz,

    1548

    00:46:59.600 --> 00:47:03.420

    I think that's it is you're going to overorder

    1549

    00:47:03.420 --> 00:47:06.240

    as a brand new provider.

    1550

    00:47:06.240 --> 00:47:08.500

    You're going to overorder if you're uncomfortable.

    1551

    00:47:08.800 --> 00:47:11.280

    But as you increase your confidence

    1552

    00:47:11.280 --> 00:47:13.820

    and I would say get a buddy on board,

    1553

    00:47:13.840 --> 00:47:15.780

    whether they're physically with you in the clinic

    1554

    00:47:15.780 --> 00:47:17.380

    or they're just a phone call away,

    1555

    00:47:18.120 --> 00:47:20.060

    that's going to increase your confidence.

    1556

    00:47:21.740 --> 00:47:23.120

    Well, can I ask briefly?

    1557

    00:47:23.320 --> 00:47:25.340

    So I actually feel way more confident with Warfarin

    1558

    00:47:25.340 --> 00:47:26.400

    than I do with the Dox

    1559

    00:47:26.400 --> 00:47:29.040

    just because that's how I came into practice was

    1560

    00:47:29.040 --> 00:47:32.140

    that's all we had because it was just too expensive.

    1561

    00:47:32.140 --> 00:47:34.040

    So I'm very comfortable with that.

    1562

    00:47:34.160 --> 00:47:37.440

    And I know, excuse me, the mentees I've worked with

    1563

    00:47:37.440 --> 00:47:39.220

    kind of like across the country, it's so different,

    1564

    00:47:39.400 --> 00:47:40.800

    whatever their comfort level is because they're like,

    1565

    00:47:40.800 --> 00:47:42.960

    oh my gosh, I've never even seen Warfarin before.

    1566

    00:47:43.020 --> 00:47:44.840

    And it's like, oh, no, no, that's literally all I do.

    1567

    00:47:45.320 --> 00:47:46.620

    So if you had somebody, for example,

    1568

    00:47:47.720 --> 00:47:50.320

    and it's so hard because I'm not in the school setting

    1569

    00:47:50.320 --> 00:47:52.400

    right now of like, what are they kind of covering?

    1570

    00:47:52.420 --> 00:47:54.440

    And I think it's different depending on the school,

    1571

    00:47:54.700 --> 00:47:57.720

    but like, yeah, I guess they could be covering this

    1572

    00:47:57.720 --> 00:47:58.320

    already in school.

    1573

    00:47:58.520 --> 00:48:01.180

    But if I'm thinking also of the people who are switching

    1574

    00:48:01.180 --> 00:48:03.440

    into practice who've been out of school for a while,

    1575

    00:48:03.660 --> 00:48:05.360

    like if you're doing like DOEX 101,

    1576

    00:48:06.740 --> 00:48:10.560

    like what are your pearls of practice that you have of like,

    1577

    00:48:10.840 --> 00:48:12.520

    so for example, if you have Warfarin,

    1578

    00:48:12.620 --> 00:48:15.440

    you have to monitor the INRs,

    1579

    00:48:15.440 --> 00:48:17.680

    it's kind of annoying for people.

    1580

    00:48:17.980 --> 00:48:19.920

    And so, yeah, like what is your decision making

    1581

    00:48:19.920 --> 00:48:21.460

    between Warfarin and DOEX?

    1582

    00:48:21.520 --> 00:48:23.640

    And then like, what are some pearls of practice

    1583

    00:48:23.640 --> 00:48:27.160

    that you have just kind of briefly about the DOEX choices

    1584

    00:48:27.160 --> 00:48:28.960

    and management of those?

    1585

    00:48:29.620 --> 00:48:31.560

    So that's a really good question

    1586

    00:48:31.560 --> 00:48:34.600

    because I tend to not have folks on,

    1587

    00:48:34.600 --> 00:48:37.240

    I'm not usually initiating the anti-guagulation

    1588

    00:48:37.240 --> 00:48:39.740

    unless they come to clinic in AFib and then I am.

    1589

    00:48:40.260 --> 00:48:41.880

    So I don't initiate for AFib,

    1590

    00:48:41.900 --> 00:48:43.900

    I don't initiate anybody on Warfarin

    1591

    00:48:43.900 --> 00:48:45.940

    because the DOEX are more affordable now.

    1592

    00:48:46.080 --> 00:48:48.740

    So that's one thing and on more formularies.

    1593

    00:48:50.260 --> 00:48:52.020

    From a Warfarin perspective,

    1594

    00:48:52.280 --> 00:48:54.320

    I manage folks who have valve disease

    1595

    00:48:54.320 --> 00:48:58.200

    and that's really mechanical valve specifically

    1596

    00:48:58.200 --> 00:49:00.620

    where I'm managing Warfarin.

    1597

    00:49:01.040 --> 00:49:02.860

    Or someone, I had somebody recently

    1598

    00:49:02.860 --> 00:49:05.100

    who has Factor V Leiden disease

    1599

    00:49:05.100 --> 00:49:09.320

    and they have DVTs and PEs ad nauseum.

    1600

    00:49:09.920 --> 00:49:12.300

    So they're just on chronic Warfarin therapy

    1601

    00:49:12.300 --> 00:49:14.800

    and they actually do their own home INRs.

    1602

    00:49:14.800 --> 00:49:15.460

    That's awesome.

    1603

    00:49:15.820 --> 00:49:16.840

    Which is wonderful.

    1604

    00:49:17.140 --> 00:49:20.180

    And this particular individual is only 38 years old.

    1605

    00:49:20.260 --> 00:49:21.720

    I had a patient like that, yeah.

    1606

    00:49:21.960 --> 00:49:22.840

    She didn't do self-titration

    1607

    00:49:22.840 --> 00:49:25.260

    but she was really young with Factor, yeah, Factor V Leiden.

    1608

    00:49:25.260 --> 00:49:27.680

    So that situation.

    1609

    00:49:28.340 --> 00:49:31.200

    What I've found and part of it is just by choice,

    1610

    00:49:31.380 --> 00:49:35.020

    a Pixaban is very safe to use.

    1611

    00:49:35.300 --> 00:49:38.140

    I've had less like GI bleeds or adverse events

    1612

    00:49:38.140 --> 00:49:40.780

    as opposed to maybe Dabigatran again.

    1613

    00:49:40.780 --> 00:49:42.520

    And then it's what I'm comfortable with.

    1614

    00:49:42.780 --> 00:49:44.660

    It's like anything, right?

    1615

    00:49:44.660 --> 00:49:47.200

    I know my anti-hypertensives I'm comfortable with.

    1616

    00:49:48.740 --> 00:49:51.920

    My SGLT2s, I would prescribe one or the other

    1617

    00:49:51.920 --> 00:49:54.940

    based on my comfort of what I've seen, right?

    1618

    00:49:55.260 --> 00:49:58.000

    The thing about a Pixaban is if renal function,

    1619

    00:49:58.020 --> 00:49:59.480

    if kidney function declines,

    1620

    00:49:59.540 --> 00:50:03.020

    you have to go from that five twice a day down to 2.5

    1621

    00:50:03.020 --> 00:50:04.560

    if they need a couple of categories.

    1622

    00:50:04.880 --> 00:50:08.480

    So I would encourage folks to pick one

    1623

    00:50:08.480 --> 00:50:10.760

    that's available on your formulary

    1624

    00:50:10.760 --> 00:50:14.220

    or the formulary of wherever your region,

    1625

    00:50:14.440 --> 00:50:16.500

    because we also know some medicines are regional

    1626

    00:50:16.500 --> 00:50:19.020

    and the bright new shiny object

    1627

    00:50:19.020 --> 00:50:20.760

    is not always the best choice.

    1628

    00:50:20.980 --> 00:50:23.160

    Get to know that medicine,

    1629

    00:50:23.160 --> 00:50:25.460

    see how your patients tolerate it.

    1630

    00:50:26.160 --> 00:50:27.720

    Because I'm often at the mercy

    1631

    00:50:27.720 --> 00:50:29.580

    of what they've started in the hospital, right?

    1632

    00:50:29.580 --> 00:50:31.300

    I see someone in a hospital follow-up

    1633

    00:50:31.300 --> 00:50:34.500

    and I'm not going to switch the Dabigatran to a Pixaban

    1634

    00:50:34.500 --> 00:50:35.520

    just because of my comfort.

    1635

    00:50:35.520 --> 00:50:36.100

    Just because you like it.

    1636

    00:50:36.100 --> 00:50:37.620

    You're on this, right, you know?

    1637

    00:50:38.100 --> 00:50:39.080

    But that's it.

    1638

    00:50:39.300 --> 00:50:41.380

    And just do the same instructions for,

    1639

    00:50:42.200 --> 00:50:44.340

    you know, I think our opportunity,

    1640

    00:50:44.380 --> 00:50:47.760

    even though I would say don't unbecome a nurse

    1641

    00:50:47.760 --> 00:50:49.100

    when I become a nurse practitioner,

    1642

    00:50:49.380 --> 00:50:50.640

    still the name is there.

    1643

    00:50:50.980 --> 00:50:52.800

    So talking about all the bleeding,

    1644

    00:50:52.800 --> 00:50:54.620

    I ask every single patient

    1645

    00:50:54.620 --> 00:50:56.420

    whether they're on a blood thinner or not

    1646

    00:50:57.040 --> 00:50:59.220

    about do you cough up blood, vomit blood,

    1647

    00:50:59.220 --> 00:51:00.400

    or see blood in the toilet?

    1648

    00:51:00.700 --> 00:51:02.700

    I have diagnosed cancer twice

    1649

    00:51:02.700 --> 00:51:04.620

    by asking just those questions.

    1650

    00:51:06.440 --> 00:51:08.860

    So really bleeding on a medicine,

    1651

    00:51:08.940 --> 00:51:09.700

    not on a medicine.

    1652

    00:51:09.960 --> 00:51:10.500

    It's easy.

    1653

    00:51:10.620 --> 00:51:11.740

    You don't have to say,

    1654

    00:51:12.040 --> 00:51:12.700

    do you help him up?

    1655

    00:51:13.000 --> 00:51:13.780

    Just says, do you help him out?

    1656

    00:51:14.420 --> 00:51:16.520

    No, cough up blood, vomit blood,

    1657

    00:51:16.540 --> 00:51:17.540

    or see blood in the toilet.

    1658

    00:51:17.640 --> 00:51:20.560

    That gives you a lot of info.

    1659

    00:51:20.860 --> 00:51:21.980

    And then, oh my gosh,

    1660

    00:51:21.980 --> 00:51:23.560

    they're on a DOAC.

    1661

    00:51:23.900 --> 00:51:25.340

    What am I going to do, right?

    1662

    00:51:25.700 --> 00:51:28.880

    And then sometimes it's the things like

    1663

    00:51:28.880 --> 00:51:31.420

    I get asked for dental extractions.

    1664

    00:51:31.600 --> 00:51:33.020

    How long should I stop it?

    1665

    00:51:33.260 --> 00:51:34.840

    I get asked for colonoscopies.

    1666

    00:51:34.900 --> 00:51:36.160

    How long should I stop it?

    1667

    00:51:37.000 --> 00:51:38.440

    No, just remember,

    1668

    00:51:38.840 --> 00:51:41.060

    most DOACs are very short-lived.

    1669

    00:51:41.340 --> 00:51:44.500

    You know, they're dosed twice a day.

    1670

    00:51:44.720 --> 00:51:46.220

    So that's how you can tell.

    1671

    00:51:46.280 --> 00:51:47.900

    They have a shorter half-life.

    1672

    00:51:48.360 --> 00:51:50.380

    So usually two days before a procedure,

    1673

    00:51:50.440 --> 00:51:51.360

    if they're stopped,

    1674

    00:51:51.360 --> 00:51:54.900

    yes, their stroke risk is higher in that little window,

    1675

    00:51:54.900 --> 00:51:56.940

    but they need the procedure, right?

    1676

    00:51:56.940 --> 00:51:59.080

    And you don't need to hemorrhage from a colonoscopy

    1677

    00:51:59.080 --> 00:52:00.320

    or a dental extraction.

    1678

    00:52:01.200 --> 00:52:02.540

    But I still look it up.

    1679

    00:52:02.720 --> 00:52:03.940

    Like, I question myself.

    1680

    00:52:04.060 --> 00:52:05.080

    Totally, totally.

    1681

    00:52:05.860 --> 00:52:07.840

    And then if it's a big surgical procedure,

    1682

    00:52:07.960 --> 00:52:09.400

    I'm like, well, geez, I don't know,

    1683

    00:52:09.400 --> 00:52:10.940

    but are they going to hypernize them

    1684

    00:52:10.940 --> 00:52:11.960

    so they're controlled?

    1685

    00:52:12.280 --> 00:52:16.280

    But they want you to make that decision.

    1686

    00:52:16.560 --> 00:52:19.460

    So don't hesitate to look it up.

    1687

    00:52:20.140 --> 00:52:21.040

    Definitely, definitely.

    1688

    00:52:21.040 --> 00:52:23.620

    Oh my gosh, this is so much fun.

    1689

    00:52:23.800 --> 00:52:26.700

    And I just want to talk to you for hours.

    1690

    00:52:27.420 --> 00:52:29.460

    But I do want to be respectful of your time.

    1691

    00:52:30.240 --> 00:52:31.000

    Thank you so much.

    1692

    00:52:31.000 --> 00:52:32.740

    This is such an honor to have you on here

    1693

    00:52:32.740 --> 00:52:34.160

    and you're such an awesome lecturer.

    1694

    00:52:34.440 --> 00:52:36.800

    Are there other conferences you're speaking at

    1695

    00:52:36.800 --> 00:52:39.840

    or is there any other place people can learn from you?

    1696

    00:52:40.240 --> 00:52:42.160

    Well, skin, bones, hearts, and private parts.

    1697

    00:52:42.440 --> 00:52:43.960

    Next year, three different times,

    1698

    00:52:44.140 --> 00:52:45.620

    I'll be doing the cardiology day.

    1699

    00:52:45.780 --> 00:52:46.400

    What is that?

    1700

    00:52:46.640 --> 00:52:48.040

    I've not heard of that conference.

    1701

    00:52:48.180 --> 00:52:49.460

    Oh my God, that's hilarious.

    1702

    00:52:49.460 --> 00:52:54.260

    It's for, Chuck Dillehy is the founder of this company

    1703

    00:52:54.260 --> 00:52:58.200

    and he asks physician assistants and nurse practitioners

    1704

    00:52:58.200 --> 00:53:00.800

    to talk to primary care audiences

    1705

    00:53:00.800 --> 00:53:05.000

    and it's called Skin, Bones, Hearts, and Private Parts

    1706

    00:53:05.000 --> 00:53:08.740

    because for a week you go to say Pensacola Beach

    1707

    00:53:08.740 --> 00:53:11.660

    or Virginia Beach and you get a day of dermatology,

    1708

    00:53:11.920 --> 00:53:16.520

    orthopedics, cardiology, bones, hearts,

    1709

    00:53:17.500 --> 00:53:18.300

    and private parts.

    1710

    00:53:18.300 --> 00:53:21.840

    So four days, G-Y-N-G-U thing.

    1711

    00:53:21.860 --> 00:53:23.940

    So it's a great way for continuing education

    1712

    00:53:23.940 --> 00:53:26.240

    but it's really geared toward it.

    1713

    00:53:26.240 --> 00:53:29.240

    So I'm covering topics like lipid management,

    1714

    00:53:29.640 --> 00:53:31.520

    what not to miss in primary care

    1715

    00:53:31.520 --> 00:53:34.060

    like aneurysms or accutum eyes,

    1716

    00:53:34.620 --> 00:53:36.220

    how to do a good telehealth visit,

    1717

    00:53:36.640 --> 00:53:38.120

    a cardiac telehealth visit, right?

    1718

    00:53:38.120 --> 00:53:38.960

    Yeah, perfect.

    1719

    00:53:39.700 --> 00:53:40.500

    Go through that.

    1720

    00:53:40.880 --> 00:53:44.140

    So I think those are some things coming up in 24.

    1721

    00:53:44.500 --> 00:53:46.940

    I've worked with this company in different regions

    1722

    00:53:46.940 --> 00:53:49.500

    but I just think, you know, reach out to me.

    1723

    00:53:49.520 --> 00:53:50.580

    Feel free to share.

    1724

    00:53:50.860 --> 00:53:53.040

    It's margaret.bowers at duke.edu.

    1725

    00:53:53.220 --> 00:53:55.440

    Oh my gosh, get ready for the influx.

    1726

    00:53:55.580 --> 00:53:56.400

    I'm okay.

    1727

    00:53:56.400 --> 00:53:58.120

    I have students all over the country

    1728

    00:53:58.120 --> 00:54:00.860

    and I think regional practices is the other thing

    1729

    00:54:00.860 --> 00:54:02.100

    we have to respect.

    1730

    00:54:02.440 --> 00:54:05.480

    And remember, we are all in this together

    1731

    00:54:05.480 --> 00:54:08.040

    to care for our patients and their loved ones, right?

    1732

    00:54:08.160 --> 00:54:09.220

    Yeah, definitely.

    1733

    00:54:09.600 --> 00:54:10.540

    That's why we do it.

    1734

    00:54:10.760 --> 00:54:12.260

    This was so much fun, Liz.

    1735

    00:54:12.500 --> 00:54:13.780

    I really can't thank you.

    1736

    00:54:13.960 --> 00:54:16.440

    I got to be real with someone and chat.

    1737

    00:54:16.980 --> 00:54:18.660

    About what I love to do.

    1738

    00:54:18.800 --> 00:54:20.460

    Well, you are welcome back any time,

    1739

    00:54:20.800 --> 00:54:22.900

    any topic you want to get on the soapbox for

    1740

    00:54:22.900 --> 00:54:23.600

    of like, priority.

    1741

    00:54:25.620 --> 00:54:26.600

    That's what I say.

    1742

    00:54:26.660 --> 00:54:29.620

    I was a critical care CNS, became an FNP

    1743

    00:54:29.620 --> 00:54:31.420

    and I love blending both worlds.

    1744

    00:54:32.060 --> 00:54:33.680

    Well, thank you so much.

    1745

    00:54:34.400 --> 00:54:36.080

    That's our episode for today.

    1746

    00:54:36.200 --> 00:54:37.960

    Thank you so much for listening.

    1747

    00:54:38.380 --> 00:54:40.700

    Make sure you subscribe, leave a review

    1748

    00:54:40.700 --> 00:54:42.580

    and tell all your NP friends.

    1749

    00:54:42.980 --> 00:54:45.540

    So together we can help as many nurse practitioners

    1750

    00:54:45.540 --> 00:54:48.300

    as possible give the best care to their patients.

    1751

    00:54:48.780 --> 00:54:50.200

    If you haven't gotten your copy

    1752

    00:54:50.200 --> 00:54:52.740

    of the ultimate resource guide for the new NP,

    1753

    00:54:53.200 --> 00:54:56.300

    head over to realworldnp.com slash guide.

    1754

    00:54:56.740 --> 00:54:58.560

    You'll get these episodes sent straight

    1755

    00:54:58.560 --> 00:55:01.340

    to your inbox every week with notes from me,

    1756

    00:55:01.720 --> 00:55:03.420

    patient stories and extra bonuses

    1757

    00:55:03.420 --> 00:55:05.580

    I really just don't share anywhere else.

    1758

    00:55:05.980 --> 00:55:07.520

    Thank you so much again for listening.

    1759

    00:55:07.680 --> 00:55:08.920

    Take care and talk soon.

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